Results 101 to 110 of about 4,447,546 (307)

Demographic and socioeconomic determinants of adherence in digital patient-reported outcomes among patients with chronic diseases

npj Digital Medicine
Engaging patients in the digital collection of electronic patient-reported outcome measures (ePROMs) and experience measures (ePREMs) is desirable for equitable, patient-centred chronic disease management; however, adherence remain unclear.
Janis Nikkhah, Alessandro Campione, Viktoria Steinbeck, Laura Wittich, Christoph Pross, Reinhard Busse   +5 more
doaj   +1 more source

Dimensions of Health Care Management Professionalization: A Scoping Review. [PDF]

Med J Islam Repub Iran, 2023
Mahmoudian P, Jafari M, De Roodenbeke E, Maleki M.   +3 more
europepmc   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Developments in hospital management: a proposal for a new hospital management model for Malta [PDF]

, 2002
The management of hospitals has changed considerably over the last two decades. The business processes and patient treatment regimes are unrecognisable from those of ten years ago.
Grech, Kenneth
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

The health Care Management of farmers who use pesticides in Northeast Brazil: use of pesticides and the Care Management. [PDF]

BMC Health Serv Res, 2023
Silverio AM, Cunha MCC, Almeida MVG.
europepmc   +1 more source

Costs and health consequences of chlamydia management strategies among pregnant women in sub-Saharan Africa [PDF]

Objectives: Chlamydia is the most common bacterial sexually transmitted infection worldwide and a major cause of morbidity – particularly among women and neonates.
Hjortdahl, Per, Hussein, Fatrima, Kristiansen, Ivar Sønbø, Romoen, Maria, Steen, Tore W., Sundby, Johanne, Velauthapillai, Manonmany   +6 more
core  

Research On Awareness Of Hospital Managers About Chronic Diseases And The Care By Multidisciplinary Teams Towards Sustainable Health Care Services In Vietnam [PDF]

, 2012
This study focused on top management in health care services in Vietnam. Kajian ini tertumpu kepada perkhidmatan penjagaan kesihatan yang diberikan oleh pengawai atasan di ...
Hayashi, Yumiko
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source