Results 61 to 70 of about 22,934,633 (247)

An integer programming model for rostering in health care organizations [PDF]

Anali Ekonomskog fakulteta u Subotici, 2014
This paper presents the development of an integer programming model as an aid to operational planning and allocation of limited human resources in health care organizations.
Marcikić Aleksandra, Čileg Marija, Radovanov Boris   +2 more
doaj  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Teamwork Approach in Lifestyle Modification in a Health Clinic: A Perspective Study

Journal of Evidence Based Health Policy, Management & Economics, 2021
Chronic diseases have become an acute challenge in health. Providing a framework for the transformation of services could be very helpful. In this study, the teamwork services based on lifestyle modification used in a series of Health Clinics in Isfahan (
Masoud Ferdosi, Majid Kolahdouzan, Behnaz Nikkar Isfahani, Arman Kolahdouzan, Mohammad Shayan Kolahdouzan   +4 more
doaj  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Perspectives of old-age and dementia researchers on communication with policymakers and public research funding decision-makers: an international cross-sectional survey

Frontiers in Medicine
IntroductionSociety commonly believes that research knowledge is complementary to public decision-making. This study aimed to understand the perspectives and implications of dementia researchers communicating with policymakers and public research ...
Peter Fusdahl, Peter Fusdahl, Miguel Germán Borda, Miguel Germán Borda, Miguel Germán Borda, Jonathan Patricio Baldera, Dag Aarsland, Dag Aarsland, Ara Khachaturian, Ara Khachaturian, Ara Khachaturian, Ara Khachaturian, Geir Sverre Braut, Geir Sverre Braut   +13 more
doaj   +1 more source

Mainstreaming Mental Health Care in 42 Countries

Health Systems & Reform, 2017
—Global consensus and national policies have emphasized deinstitutionalization, or a shift in providing mental health care from institutional to community settings.
Gordon C. Shen, Julian Eaton, Lonnie R. Snowden   +2 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

An evolved perspective on critical thinking in health care managers: A concept analysis

Chronic Diseases Journal
Background: Leaders are tasked with making decisions that have substantial impact on an organization's well-being. Decision making requires critical thinking. Clinical environments are becoming more complex and demanding nowadays. Acquisition of critical
Hussein Saber Hussein, Kaveh Bahmanpour, Mohammad Fathi, Adel Fatemi   +3 more
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Cases in Health Care Management

, 2014
Summary: From the authors of the bestselling Introduction to Health Care Management comes this compendium of 101 case studies that illustrate the challenges related to managing healthcare services.
Shanks, Nancy H., Buchbinder, Sharon B, Buchbinder, Dale   +2 more
core   +1 more source