Results 111 to 120 of about 918,627 (316)

Pre-validation methods for developing a patient reported outcome instrument [PDF]

, 2011
Background: Measures that reflect patients' assessment of their health are of increasing importance as outcome measures in randomised controlled trials.
Ramsay, Craig R, Burr, JM, Hamzah, J. C., Burr Jennifer M, Susan E Campbell, Francis, JJ, Prior, M., Che Hamzah, Jemaima, Azuara-Blanco, Augusto; id_orcid, Campbell, S. E., Castillo, MM, Prior Maria E, Maria E Prior, Castillo, Mayret M, Hamzah, Jemaima Che, Francis, Jillian J., Ramsay, CR, Prior, Maria E, Hamzah, JC, Campbell Susan E, Campbell, SE, Francis, Jillian J, Jemaima Che Hamzah, Prior, Maria E., Azuara-Blanco, A., Mayret M Castillo, Ramsay, Craig R., Ramsay, C. R., Castillo Mayret M, Francis, J., Castillo, M, Castillo, Mayret M., Burr, J. M., Prior, ME, Campbell, Susan E, Jillian J Francis, Craig R Ramsay, Burr, Jennifer M., Jennifer M Burr, Azuara-Blanco, A, Azuara-Blanco, Augusto, Burr, Jennifer M, Campbell, Susan E., Francis Jillian J, Hamzah Jemaima, Ramsay Craig R, Augusto Azuara-Blanco, Azuara-Blanco Augusto   +47 more
core   +1 more source

Impacto en los resultados en salud de la telesalud aplicada para la atención y seguimiento ambulatorio del alto riesgo obstétrico: revisión narrativa de la literatura

Medicina U.P.B.
Esta revisión examina la literatura sobre el impacto de la telesalud aplicada en modelos de atención en salud ambulatorios sobre los resultados en salud (funcionales, costos, satisfacción y calidad de vida) en población gestante de alto riesgo.
Sara Arango Valencia, Juan Guillermo Barrientos, Ever Augusto Torres Silva, Emmanuel Sánchez Diaz   +3 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Identification of depressive disorder among older people in care homes – a feasibility study

, 2011
Background: Depression is common among older people but more common among those living in care homes. Depression is not easily detected among older adults because of the presentation, and the tendency for older people not to complain of depression ...
Shaik, K, Stephenson, John, C. Jane Morrell, Kauserjan Shaik, Muthukrishnan, Venkatesh, Curran, Stephen, Curran, S, Morrell, C. Jane, Venkatesh Muthukrishnan, Topping, Annie, Annie Topping, Morrell, CJ, Topping, A; id_orcid, John Stephenson, Muthukrishnan, V, Stephenson, J, Shaik, Kauserjan, Stephen Curran   +17 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Disparities in the protagonism of oral health teams in the work process of Primary Healthcare [PDF]

Revista de Saúde Pública
OBJECTIVE Evaluate and compare the protagonism of Oral Health teams (OHt) in the teamwork process in Primary Healthcare (PHC) over five years and estimate the magnitude of disparities between Brazilian macro-regions. METHODS Ecological study that used
Érika Talita Silva, Raquel Conceição Ferreira, Fabiano Costa Diniz, Milena Ribeiro Gomes, Andréa Maria Eleutério de Barros Lima Martins, Loliza Luiz Figueiredo Houri Chalub, Maria Inês Barreiros Senna   +6 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

The UPBEAT nurse-delivered personalized care intervention for people with coronary heart disease who report current chest pain and depression: a randomised controlled pilot study [PDF]

, 2014
Background: Depression is common in people with coronary heart disease (CHD) and associated with worse outcome. This study explored the acceptability and feasibility of procedures for a trial and for an intervention, including its potential costs, to ...
Phillips, Rachel, Mark Haddad, van Marwijk, Harm, Van Marwijk Harm, Rachel Phillips (469282), Paul McCrone, van Marwijk, H.W.J., Barley, Elizabeth A, Barley Elizabeth A., Mark Haddad (469281), Tylee, Andre, Anthony Mann (469284), Haddad, M., Phillips Rachel, Barley, Elizabeth A., Phillips, Rachel; id_orcid, Barley, Elizabeth, Achilla, Evanthia, Mann, A., Andre Tylee, Walters, P., Anthony Mann, Tylee Andre, Elizabeth A Barley, Achilla, E., Mann, Anthony, Rachel Phillips, McCrone Paul, Barley, E. A., Van Marwijk, H., Tylee, A., Achilla Evanthia, Paul Walters (349725), Elizabeth A. Barley (573572), Harm Van Marwijk, Haddad Mark, Evanthia Achilla (573573), Paul McCrone (121370), Paul Walters, Phillips, R., Walters, Paul, Haddad, Mark, Evanthia Achilla, Walters Paul, Mann Anthony, McCrone, P., Andre Tylee (3146625), McCrone, Paul, Harm Van Marwijk (573574), Barley, E.A.   +49 more
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Quality of longer term mental health facilities in Europe: validation of the quality indicator for rehabilitative care against service users' views. [PDF]

, 2012
BACKGROUND: The Quality Indicator for Rehabilitative Care (QuIRC) is a staff rated, international toolkit that assesses care in longer term hospital and community based mental health facilities.
Alexiev Spiridon, Visser Ellen, Raboch Jiri, Almeida, José Miguel Barros Caldas de, Thomas Kallert, Durk Wiersma, Alexiev, Spiridon, Gonidakis, F, Cervilla Jorge A., Cardoso, Graça Maria Pereira, Caldas-de-Almeida, JM, Georgi Onchev, Mezzina Roberto, Raboch, J, Gonidakis, Fragiskos, Cervilla, Jorge A, Ridente, P, Raboch, Jiri, Visser, Ellen; id_orcid, Brangier, Paulette, Kalisova, Lucie, Patryk Piotrowski, Wiersma Durk, King, Michael, Visser, E, Kiejna, Andrzej, Penny Turton, Taylor, Tatiana L., Alexiev, S, Wright Christine, Pina Ridente, Wiersma, D, Mirjam Schuster, Ellen Visser, Christine Wright, José Miguel Caldas-de-Almeida, Tatiana L. Taylor, Killaspy, Helen, Lucie Kalisova, Brangier, P, Ploumpidis, Dimitris, Ridente, Pina, Paulette Brangier, Taylor Tatiana L., Kallert Thomas, Wright, Christine, Piotrowski, Patryk, Caldas-de-Almeida José Miguel, Helen Killaspy, Sarah White, White, S, Mezzina, R, Turton, P, Ridente Pina, Schuster, Mirjam, Jiri Raboch, Jorge A. Cervilla, Cervilla, Jorge A., Onchev, Georgi, Cardoso Graça, Kalisova, L, Visser, Ellen, Dimitris Ploumpidis, Brangier Paulette, Ploumpidis Dimitris, Kiejna Andrzej, Mezzina, Roberto, Fragiskos Gonidakis, King, M, Tatiana L Taylor, Killaspy, H, Wright, C, Taylor, Tatiana L; id_orcid, Onchev Georgi, Helen Killaspy, Kiejna, A, Ploumpidis, D, Piotrowski, P, Jorge A Cervilla, King Michael, Wiersma, Durk, Kalisova Lucie, Cardoso, Graça, Schuster, M, White Sarah, Caldas-de-Almeida, José Miguel, Schuster Mirjam, Cardoso, G, Andrzej Kiejna, Gonidakis Fragiskos, White, Sarah, Cervilla, JA, Spiridon Alexiev, Taylor, Tatiana L, Kallert, T, Piotrowski Patryk, Turton Penny, Turton, Penny, Kallert, Thomas, Taylor, TL, Onchev, G, Michael King, Roberto Mezzina, Graça Cardoso, Killaspy Helen   +104 more
core   +1 more source