Results 91 to 100 of about 918,627 (316)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Can the shift from needs-led to outcomes-focused assessment in health and social care deliver on policy priorities?

, 2010
Assessment, planning and review are at the heart of the provision of services and support in health and social care in the community, providing key means through which professionals interact with people using their services.
Miller, Emma
core  

Fatores associados à percepção de melhora por usuários de Centros de Atenção Psicossocial do Sul do Brasil

Cadernos de Saúde Pública
Este estudo objetivou investigar os fatores associados à melhora percebida pelos usuários de Centros de Atenção Psicossocial (CAPS). Estudo transversal, realizado com 1.493 usuários de CAPS do Sul do Brasil.
Uiasser Thomas Franzmann, Luciane Prado Kantorski, Vanda Maria da Rosa Jardim, Carlos Alberto dos Santos Treichel, Michele Mandagará de Oliveira, Fabiane Machado Pavani   +5 more
doaj   +1 more source

Prognostic value of urethral mobility and valsalva leak point pressure for female transobturator sling procedure

International Brazilian Journal of Urology, 2012
PURPOSE: To analyze the influence of urethral mobility and Valsalva leak point pressure on postoperative outcomes of transobturator sling (TOT) for female stress urinary incontinence. MATERIALS AND METHODS: A prospective cohort was conducted including 66
Luis Gustavo Morato de Toledo, Pedro Henrique Oliveira Cabral, Mário Luís Casella, Gabriel Elias Politi, Sandro Nasser Cardoso, Luiz Figueiredo Mello, Sidney Glina   +6 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Factors affecting hospital discharge in maxillofacial trauma patients: a retrospective study

Brazilian Journal of Oral Sciences, 2017
Aim: To determine factors that may affect the time of discharge from hospital in patients who underwent maxillofacial trauma. Methods: The sample included 115 patients seen at a public hospital in Brazil, to whom surgical maxillofacial treatment was ...
Leonardo Victor Galvão-Moreira, Andre Luis Costa Cantanhede, Aluisio Cruz de Sousa Neto, Maria Carmen Fontoura Nogueira da Cruz   +3 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Protocol for the Foot in Juvenile Idiopathic Arthritis trial (FiJIA): a randomised controlled trial of an integrated foot care programme for foot problems in JIA [PDF]

, 2009
<b>Background</b>: Foot and ankle problems are a common but relatively neglected manifestation of juvenile idiopathic arthritis. Studies of medical and non-medical interventions have shown that clinical outcome measures can be improved ...
Sturrock, R.D., Hendry Gordon J, McColl, John, Sturrock Roger D, Lorgelly Paula K, Woodburn Jim, Woodburn, J., McColl John, Sturrock, Roger, Gardner-Medwin, J., Gardner-Medwin Janet, Turner, Deborah E., Browne, Michael, Turner, Deborah, Browne Michael, Hendry, Gordon, Lorgelly, Paula K., Hendry, Gordon J., Lorgelly, Paula, Sturrock, Roger D., Woodburn, James, Watt Gordon F, Gardner-Medwin, Janet, Hendry, Gordon; id_orcid, Browne, M., Turner Deborah E, Friel, L., Turner, D.E., Watt, Gordon, Friel, Lorraine, Hendry, G.J., Friel Lorraine, McColl, J., Lorgelly, P., Watt, G.F., Watt, Gordon F.   +35 more
core   +1 more source

Avaliação dos resultados de intervenção após mudanças realizadas nos cuidados peri-operatórios em pacientes submetidos a operações abdominais eletivas

Revista do Colégio Brasileiro de Cirurgiões
OBJETIVO: Avaliar os resultados da introdução de novas medidas visando acelerar a recuperação pós-operatória de pacientes submetidos à cirurgia abdominal eletiva.
Mayra da Rosa Martins Walczewski, Ariane Zanetta Justino, Eduardo André Bracci Walczewski, Tatiane Coan   +3 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source