Results 71 to 80 of about 26,804,747 (294)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Other title: Policies and Procedures : for Administration of the Health Care Provider Insurance Availability Act; Other title: Administration of the Health Care Provider Insurance Availability Act

, 2017
[Revised].; "Adopted March 6, 2008. Amended July 10, 2008; July 9, 2009; May 13, 2010; Nov. 18, 2010; July 10, 2014; Sep. 10, 2015; May 11, 2017; September 14, 2017.""The Kansas Health Care Stabilization Fund was created in 1976 by enactment of the ...
Kansas. Board of Governors of the Health Care Stabilization Fund.
core   +1 more source

Challenges of Health Technology Incubators in Iran: A Qualitative Study

Journal of Evidence Based Health Policy, Management & Economics, 2019
Background: Health Technology Incubators (HTI) play an important role in paving the way depicted in Iran’s comprehensive health plan in order to achieve the aimed position in 2025.
Mohammad Ali Moghbeli, Ali Reza Kalantari, Somayeh Noori Hekmat, Mahshid Salemian pour, Ehsan Lorafshar, Mohammad Saleh Koushki, Reza Dehnavieh   +6 more
doaj  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Other title: Availability and utilization of health care services at acute care hospitals and federally qualified health centers fiscal year 2010

, 2011
"As required by Connecticut General Statutes (C.G.S.) section 19a-634 this report is one of three components of the Department of Public (DPH) Health Office of Health Care Access' (OHCA) approach to planning for Connecticut's health care system"--P. 4.; "

core  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

An exploration of patients’ experience of nurses’ use of point-of-care information technology in acute care

Patient Experience Journal, 2018
The rapid introduction of technology into acute healthcare settings, specifically the presence of point-of-care health information technology at patients’ bedsides, is expected to impact patients’ healthcare experience by altering nurse-patient ...
Leigh McNicol, Anastasia Hutchinson, Beverley Wood, Mari Botti, Bernice Redley   +4 more
doaj  

The Healthcare Future for the iGeneration: Integrating the Patient and the Healthcare System

INNOVATIONS in Pharmacy, 2013
Objective: To propose a vision to integrate patients, their health-related data, and their wellness plans into the healthcare system using smartphone and tablet computer technology.
Kristina D. Wood, Elisa M. Greene, Rachel B. Franks, Traci M. Poole, Cathy H. Ficzere, Philip E. Johnston   +5 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source