Results 31 to 40 of about 12,661,805 (254)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Sugar‐free hard confectionery with at least 90% erythritol and reduction of dental plaque which reduces the risk of dental caries: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006

EFSA Journal, 2017
Following an application from Cargill R&D Centre Europe, submitted for authorisation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006 via the Competent Authority of Belgium, the EFSA Panel on Dietetic Products, Nutrition and ...
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA), Dominique Turck, Jean‐Louis Bresson, Barbara Burlingame, Tara Dean, Susan Fairweather‐Tait, Marina Heinonen, Karen Ildico Hirsch‐Ernst, Inge Mangelsdorf, Harry J McArdle, Androniki Naska, Monika Neuhäuser‐Berthold, Grażyna Nowicka, Kristina Pentieva, Yolanda Sanz, Anders Sjödin, Martin Stern, Daniel Tomé, Henk Van Loveren, Marco Vinceti, Peter Willatts, Ambroise Martin, John Joseph Strain, Alfonso Siani   +23 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Deep learning-based multiclass segmentation in aneurysmal subarachnoid hemorrhage

Frontiers in Neurology
IntroductionRadiological scores used to assess the extent of subarachnoid hemorrhage are limited by intrarater and interrater variability and do not utilize all available information from the imaging. Image segmentation enables precise identification and
Julia Kiewitz, Julia Kiewitz, Orhun Utku Aydin, Adam Hilbert, Marie Gultom, Anouar Nouri, Ahmed A. Khalil, Peter Vajkoczy, Satoru Tanioka, Fujimaro Ishida, Nora F. Dengler, Nora F. Dengler, Nora F. Dengler, Dietmar Frey, Dietmar Frey   +14 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The Serbian functional food market: Does regulation make a difference? [PDF]

Ekonomski Anali, 2012
This paper focuses on empirical analysis of the Serbian functional food market and its comparison with those in other Western Balkan countries (WBC).
Stojanović Žaklina, Dragutinović-Mitrović Radmila   +1 more
doaj   +1 more source

A New Definition of the Term “High-Phenolic Olive Oil” Based on Large Scale Statistical Data of Greek Olive Oils Analyzed by qNMR

Molecules, 2021
In the last few years, a new term, “High-phenolic olive oil”, has appeared in scientific literature and in the market. However, there is no available definition of that term regarding the concentration limits of the phenolic ingredients of olive oil. For
Panagiotis Diamantakos, Kostas Ioannidis, Christos Papanikolaou, Annia Tsolakou, Aimilia Rigakou, Eleni Melliou, Prokopios Magiatis   +6 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Comparative analysis of regulatory frameworks for domestic and international food claims

Zhongguo shipin weisheng zazhi
ObjectiveThis study examined the regulatory frameworks of food claims established by the Codex Alimentarius Commission （CAC）， the European Union （EU）， the United States， Canada， Australia and New Zealand， and Japan. Concurrently， the survey on the demand
LYU Xueli, YU Hangyu, ZHU Lei, FAN Yongxiang   +3 more
doaj   +1 more source

A fixed carbohydrate:protein ratio ≤ 1.8 on an energy basis consumed in the context of an energy‐restricted diet and reduction of body weight: evaluation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006

EFSA Journal, 2017
Following an application from Marks and Spencer PLC, submitted for authorisation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of the United Kingdom, the EFSA Panel on Dietetic Products, Nutrition
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA), Dominique Turck, Jean‐Louis Bresson, Barbara Burlingame, Tara Dean, Susan Fairweather‐Tait, Marina Heinonen, Karen Ildico Hirsch‐Ernst, Inge Mangelsdorf, Harry J McArdle, Androniki Naska, Monika Neuhäuser‐Berthold, Grażyna Nowicka, Kristina Pentieva, Yolanda Sanz, Anders Sjödin, Martin Stern, Daniel Tomé, Henk Van Loveren, Marco Vinceti, Peter Willatts, Ambroise Martin, John Joseph Strain, Alfonso Siani   +23 more
doaj   +1 more source