Results 111 to 120 of about 1,413,593 (317)

Understanding leadership challenges faced by humanitarian aid workers: insights from the experiences of NNPHL training participants

Journal of International Humanitarian Action
This paper examines the self-reported leadership challenges experienced by humanitarian aid workers who participated in the National NGO Program on Humanitarian Leadership (NNPHL) Program.
Godfred Nyarko, Ariana Marnicio, Vincenzo Bollettino   +2 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

On environmental concern, willingness to pay, and postmaterialist values: Evidence from Istanbul

We explore the impact of geographical proximity of environmental problems on environmental concern and willingness to pay (WTP) for environmental improvement, with emphasis on the relevance of Inglehart’s postmaterialism thesis on this inquiry.
Gökşen, Fatoş, Zenginobuz, Unal, Adaman, Fikret   +2 more
core  

Expanding Concern for Women's Health in Developing Countries. The Case of the Eastern Mediterranean Region

, 2010
Background: Women's health is still largely associated with the notion of reproduction in developing countries despite a more varied disease burden, including noncommunicable conditions resulting from consequences of changing epidemiologic and ...
Zurayk H., Saliba M.
core   +1 more source

Tradition, taste and taboo: the gastroecology of maternal perinatal diet

BMJ Nutrition, Prevention & Health
Background Maternal malnutrition is a major source of regional health inequity and contributes to maternal and infant morbidity and mortality. Bihar, a state in eastern India adjacent to Jharkhand and West Bengal, has relatively high neonatal mortality ...
Indrajit Chaudhuri, Sudipta Mondal, Hannah G Lunkenheimer, Oskar Burger, Santosh Akhauri, Lisa Dibbell, Faiz A Hashmi, Tracy Johnson, Emily E Little, Nachiket Mor, Neela Saldanha, Janine Schooley, Cristine H Legare   +12 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Alcohol services and mental health planning

, 2003
Includes bibliographical referencesAvailable from British Library Document Supply Centre- DSC:2283.
Alcohol Concern. Mental Health and Alcohol Misuse Project (United Kingdom)
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source