Results 121 to 130 of about 1,413,593 (317)

Validating mental well-being items of the Scottish Health Behaviour in School-aged Children (HBSC) Survey

, 2010
This research was funded by NHS Health Scotland as a developmental part of the national HBSC ...
Muldoon, Janine Claire, Levin, Kate, van der Sluijs, Winfried, Muldoon, Janine, Currie, Candace   +4 more
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Mental Health and Alcohol Misuse Project Factsheet : the Mental Health National Framework Service

, 2002
Includes bibliographical references. Title from coverAvailable from British Library Document Supply Centre- DSC:m03/10664 / BLDSC - British Library Document Supply CentreSIGLEGBUnited ...
Alcohol Concern (United Kingdom)
core  

Disasters and Public Health Concerns [PDF]

Asia Pacific Journal of Public Health, 2011
Low, W., Binns, Colin
openaire   +3 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

The prevention of transmission of blood-borne diseases in the health-care setting

, 2006
  The risk of transmission of blood-borne pathogens in the health-care setting has become a matter of increasing concern in Ireland in recent years.
Department of Health (Ireland)
core   +1 more source

Developing a tool to facilitate person-centered care in a university hospital in collaboration with patients and healthcare professionals

BMC Health Services Research
Background Person-centered care (PCC) aims to treat patients as full persons and provide care that fits patients’ contexts, needs, and wishes. This healthcare approach views patients as active partners, emphasizing patient engagement. PCC is increasingly
L. A. de Keizer, J. H. K. Bergers, H. Wessels-Wynia, J. J. M. van Delden, A. Janssens   +4 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source