Results 101 to 110 of about 8,196,694 (316)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Le régime des traitements de données de santé : une réflexion à l’aune de trois délibérations de la CNIL

open access: yesCahiers Droit, Sciences & Technologies
The analysis of the legal framework for two specific health data processings, i. e. fortune telling consultation and health data warehouses, invites us to globally consider the law on health data processings.
Rebecca Demoule
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Data Fit for Health Equity: Learning Health Systems, AI, and the STANDING Together Recommendations

open access: yesLearning Health Systems
Introduction Artificial Intelligence (AI) tools may deliver significant improvements in healthcare and Learning Health Systems are well positioned to benefit.
Elinor Laws, Neil Cockburn
doaj   +1 more source

Data Visualization and Health Econometrics [PDF]

open access: yesFoundations and Trends® in Econometrics, 2017
This article reviews econometric methods for health outcomes and health care costs that are used for prediction and forecasting, risk adjustment, resource allocation, technology assessment, and policy evaluation. It focuses on the principles and practical application of data visualization and statistical graphics and how these can enhance applied ...
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Big data and health [PDF]

open access: yesThe Lancet Digital Health, 2019
Michael, Snyder, Wenyu, Zhou
openaire   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Community Health Centre Report

open access: yes, 2016
The Northern Territory Aboriginal Health Forum (NT AHF), that comprises representatives from the Commonwealth Department of Health (DoH), Aboriginal Medical Services Alliance of the Northern Territory (AMSANT) and the Northern Territory Department of ...
Data Management & System Reporting
core  

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