Results 111 to 120 of about 8,196,694 (316)
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
IoMT and Blockchain Synergy: A Novel Approach to Health Data Validation and Storage
IEEE AccessThe increasing adoption of Internet of Medical Things (IoMT) devices is revolutionizing healthcare, facilitating enhanced remote patient monitoring and data-driven clinical decision-making.
Abbas Syed Muhammad Ali +4 more
doaj +1 more source
HEALTH+: Empowering Individuals via Unifying Health Data
Proceedings of the 33rd ACM International Conference on MultimediaManaging personal health data is a challenge in today's fragmented and institution-centric healthcare ecosystem. Individuals often lack meaningful control over their medical records, which are scattered across incompatible systems and formats. This vision paper presents Health+, a user-centric, multimodal health data management system that empowers ...
Sujaya Maiyya +2 more
openaire +2 more sources
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Health data sharing in Germany: individual preconditions, trust and motives
Frontiers in Public HealthObjectiveThe use of health data plays an important role in medical research. In Germany, the secondary use of health data is not yet as established as in other countries.
Elias Kühnel, Felix Wilke
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
, 2020 This study consists of information from all five surveys of the 1989-95 cohort. In 2012 and 2013, 17,010 18-23 year old women were enrolled in this cohort. Women were mainly recruited using the internet and social media platforms.
Mishra, Gita +4 more
core +1 more source
A Study on the European Union's Secondary Use System of Health Data and Its Insights
Yixue yu zhexueThe effective utilization of health data not only contributes to improve the treatment quality for individual patients，but also promotes the efficient realization of public interests in areas such as healthcare governance, medical research, and public ...
Yao PAN
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source