Results 171 to 180 of about 41,358,503 (314)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
NT Aboriginal Health Key Performance Indicators - Data Receiving Protocol
The Northern Territory Aboriginal Health Key Performance Indicator Information System (NT AHKPI) provides information on and collaboration between both government and non-government health services for reporting key performance indicator (KPI) data on ...
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
The Public Health Data Strategy [PDF]
Updated April 11, 2024At a Glance: The PHDS is CDC\u2019s mission-focused, goal-driven, two-year plan providing accountability for data, technology, policy and administrative actions necessary to meet public health data goals.
core
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Editorial: Health data science and AI in neuroscience & psychology. [PDF]
Lu L, Huo Z, Li J, Zhao E.
europepmc +1 more source
Client/Partner: National Alliance of State and Territorial AIDS DirectorsThis toolkit for the National Alliance of State and Territorial AIDS Directors provides a list of diagnosis, procedure, and prescription drug codes to help health departments ...
Leary, Amy +5 more
core
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
2023 Canadian Digital Health Survey
The Canadian Digital Health Survey is a series of surveys conducted annually commissioned by Canada Health Infoway (Infoway) through a third-party vendor.
Canada Health Infoway
core +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source

