Results 181 to 190 of about 8,196,694 (316)

VSUS. Part 1, Natality

, 1994
Print began with 1937.; Imprint varies: Washington, D.C., ; Hyattsville, Md., -; Vols. for 199 -1993 include technical appendixes; vols. for 1994- accompanied by technical appendix, with title : Technical appendix from Vital statistics of the United ...
National Center for Health Statistics (U.S.). Division of Data Services.
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HealthData@MAD-R&I: Protocol for Design and Development of a Regional Health Data Infrastructure to Enable Secondary Use of Health Data in Research and Innovation. [PDF]

JMIR Res Protoc
León-García M, Álvarez-Pérez S, Gesto-Gómez J, Urbano-Molina C, Soto-Díaz S, Cárdenas-Valladolid J, Rodríguez-Rodríguez L, Díaz-Holgado A, Del Cura-González I, De La Cruz-Bertolo J, García-Barrio N, Cruz-Bermúdez JL, García-Fernández C, Rodríguez-Antolín C, García-Aldars L, Moreda-Sánchez EM, Roldán López Á, Veganzones Alonso-Cortés JM, Gonzalez Gonzalez AI, Salinero-Fort MA, HealthData@MAD-R&I Working Group.   +20 more
europepmc   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Building Public Health Data Dashboards: Tutorial Playbook. [PDF]

JMIR Public Health Surveill
Wu E, Balise R, Katz B, Harris D, Bullard M, Fareed N, Larochelle M, Villani J.   +7 more
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Quantifying effects of the European Health Data Space on the app ecosystem and data access. [PDF]

NPJ Digit Med
Brückner S, Riedel R, Hetmank S, Fritsch K, Freyer O, Gilbert S.   +5 more
europepmc   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Public health data strategy : public health data goals and 2-year milestones

The Public Health Data Strategy (PHDS) outlines the data, technology, policy, and administrative actions essential to exchange critical core data efficiently and securely across healthcare and public health.The strategy is designed to describe a path to ...

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