Results 31 to 40 of about 387,344 (292)

Modeling of the HIV infection epidemic in the Netherlands: A multi-parameter evidence synthesis approach

, 2012
Multi-parameter evidence synthesis (MPES) is receiving growing attention from the epidemiological community as a coherent and flexible analytical framework to accommodate a disparate body of evidence available to inform disease incidence and prevalence ...
Conti, Stefano, De Angelis, Daniela, Donoghoe, Martin C., Presanis, Anne M., Stengaard, Annemarie Rinder, van Veen, Maaike G., Xiridou, Maria   +6 more
core   +1 more source

Risk Equity: A New Proposal [PDF]

, 2007
What does distributive justice require of risk regulators? Various executive orders enjoin health and safety regulators to take account of “distributive impacts,” “equity,” or “environmental justice,” and many scholars endorse these requirements.
Adler, Matthew D.
core   +3 more sources

Identifying and addressing disparities in the evaluation and treatment of children with growth hormone deficiency

Frontiers in Endocrinology, 2022
Health disparities are a significant cause of concern globally and in the United States. Disparities have been additionally highlighted throughout the ongoing COVID-19 pandemic during which populations of color have been the most affected by the disease.
Kara Beliard, Vickie Wu, Julie Samuels, Terri H. Lipman, Robert Rapaport   +4 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Is younger really safer? A qualitative study of perceived risks and benefits of age-disparate relationships among women in Cape Town, South Africa.

PLoS ONE, 2013
Young women in age-asymmetric relationships may be at an elevated risk for acquisition of HIV, since relationships with older men are also correlated with other risk behaviors like less condom use.
Roxanne Beauclair, Wim Delva
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

A case for using grid architecture for state public health informatics: the Utah perspective

BMC Medical Informatics and Decision Making, 2009
This paper presents the rationale for designing and implementing the next-generation of public health information systems using grid computing concepts and tools.
Rolfs Robert, Gundlapalli Adi, Narus Scott P, Price Ronald C, LeFevre Samuel D, Xu Wu, Staes Catherine J, Nangle Barry, Samore Matthew, Facelli Julio C   +9 more
doaj   +1 more source

Demonstrating a systems approach for integrating disparate data streams to inform decisions on children’s environmental health

BMC Public Health, 2022
Background The use of systems science methodologies to understand complex environmental and human health relationships is increasing. Requirements for advanced datasets, models, and expertise limit current application of these approaches by many ...
Elaine A Cohen Hubal, Nicole M DeLuca, Ashley Mullikin, Rachel Slover, John C Little, David M Reif   +5 more
doaj   +1 more source

State-of-the-Art Review on the Application of Membrane Bioreactors for Molecular Micro-Contaminant Removal from Aquatic Environment

Membranes, 2022
In recent years, the emergence of disparate micro-contaminants in aquatic environments such as water/wastewater sources has eventuated in serious concerns about humans’ health all over the world.
My-Linh Nguyen, Ali Taghvaie Nakhjiri, Mehnaz Kamal, Abdullah Mohamed, Mohammed Algarni, Subbotina Tatyana Yu, Fu-Ming Wang, Chia-Hung Su   +7 more
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source