Results 81 to 90 of about 202,216 (259)

Personal, health system, and geosocial disparities in appointment nonadherence at family medicine clinics in southcentral Pennsylvania, United States

Journal of General and Family Medicine
Background To assess the relationship between patients' demographic, health system‐related, and geosocial characteristics and the risk of missed appointments among patients in family medicine practice. Methods The study was based on a retrospective cross‐
Wen‐Jan Tuan, Ashley Weems, Shou Ling Leong   +2 more
doaj   +1 more source

Associations between socioeconomic factors and mental symptoms highlight whole-body correlates and pathways

iScience
Summary: Socioeconomic status (SES) correlates with both mental symptoms and systemic health traits, suggesting systemic health conditions as potential complementary pathways for SES-mental health associations alongside neural mechanisms.
Guoshu Zhao, Jie Tang, Zehao Wang, Qian Qian, Shaoying Wang, Nannan Zhang, Jinghan Sun, Hui Xue, Zuhao Sun, Yingying Xie, Zirui Wang, Huaigui Liu, Hao Ding, Feng Liu, Wen Qin, Meng Liang, Jiayuan Xu, Chunshui Yu   +17 more
doaj   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

NF-κB and STAT3 signaling uniquely stratify survival in female glioblastoma patients

iScience
Summary: The mechanisms underlying sex differences in glioblastoma (GBM) incidence, treatment response, and survival are not well understood. Increased activation of nuclear factor-kappa B (NF-κB) and signal transducer and activator of transcription 3 ...
Jason P. Wong, Lorida Llaci, Lloyd Tripp, Myung Sik Jeon, Lihua Yang, Nicholas Reinhold, Nicole M. Warrington, Jingqin Luo, Robi D. Mitra, Joshua B. Rubin   +9 more
doaj   +1 more source

Validating the HELP Survey to Understand Health Disparity Influence on Chronic Pain

Journal of Pain Research, 2022
Monika Patel,1 Sophia Sheikh,2 Jennifer Brailsford3 1Department of Anesthesiology, Division of Pain Management, University of Florida College of Medicine, Jacksonville, FL, USA; 2Department of Emergency Medicine, University of Florida College of Medicine,
Patel M, Sheikh S, Brailsford J
doaj  

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source

Comprehensive Characterization of 98 Chinese Cases of Genetic Creutzfeldt‐Jakob Disease With T188K Mutation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li, Dong‐Lin Liang, Li‐Ping Gao, Wei‐Wei Zhang, Wei Zhou, A. Ruhan, Bing Xu, Run‐Dong Cao, Kang Xiao, Cao Chen, Qi Shi, Xiao‐Ping Dong   +11 more
wiley   +1 more source

Global Rather Than Vertical‐Selective Saccadic Abnormalities in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To test whether vertical saccades are preferentially affected in Progressive Supranuclear Palsy (PSP). Methods PSP patients (n = 24) were compared to age‐matched controls (n = 94) and two degenerative groups (Alzheimer's disease, n = 20; Lewy body disease, n = 50).
Duy Duan Nguyen, Mark Paine, Soohyun Lee, Amir Fazlollahi, Baibin (Ben) Wang, John D. O'Sullivan, Peter J. Nestor   +6 more
wiley   +1 more source

The Price of Precision: A Critical Review of Molecular Diagnostics in Glioma, From Guidelines to Global Disparities

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
wiley   +1 more source

Early‐onset triple‐negative breast cancer in multiracial/ethnic populations: Distinct trends of prevalence of truncation mutations

Cancer Medicine, 2019
Young black women are at higher risk of triple‐negative breast cancer (TNBC); however, a majority of the genetic studies on cancer predisposition were carried out in White populations.
Qian Liu, Song Yao, Hua Zhao, Qiang Hu, Marilyn L. Kwan, Janise M. Roh, Christine B. Ambrosone, Lawrence H. Kushi, Song Liu, Qianqian Zhu   +9 more
doaj   +1 more source