Results 121 to 130 of about 20,751,393 (307)

Kidney Health for All: Bridging the Gap in Kidney Health Education and Literacy

Turkish Journal of Nephrology, 2022
Robyn G. Langham, Kamyar Kalantar-Zadeh, Ann Bonner , Alessandro Balducci , Li-Li Hsiao, Latha A. Kumaraswami , Paul Laffin, Vassilios Liakopoulos, Gamal Saadi, Ekamol Tantisattamo, Ifeoma Ulasi , Siu-Fai Lui , for the World Kidney Day Joint Steering Committee   +12 more
doaj   +1 more source

Cultural and linguistic adaptation of stop the bleed: saving lives in a multi-ethnic refugee resettlement community

Health Literacy and Communication Open
Background Research and practice show an urgent need for health interventions to be adapted in culturally and linguistically responsive ways for limited English proficient (LEP) communities where cultural and language discordance exacerbate challenges in
Iris Feinberg, Randi N. Smith, Amy Zeidan, Deepika Kogonti, Kelleigh Dawn Trepanier, Stephanie Adrian, Mary Helen O’Connor   +6 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Effectiveness of Structured Teaching Program on Adolescent’s Knowledge of Tobacco Consumption: A Randomized Control Trial

Journal of Pharmacy and Bioallied Sciences
Aim and Objective: The aim of the article is to determine the effectiveness of a structured teaching program on knowledge of tobacco consumption and its effects among adolescents (age group 13–16-year boys) and its retention over a period of six months ...
Prasanta Majumder, Pallavi A. Thomas, Vaibhav Motghare, Pranav V. Manek, Lubna Nazneen, Suchetana Basak, Sheetal Acharya   +6 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Other title: Health Education Guidelines

, 1993
"June 1991. Third reprint September, 1993." "This document was completed with support provided by a cooperative agreement (#U63/CCU703078-02) with the Division of Adolescent and School Health, Center for Chronic Disease Prevention and Health Promotion ...
Kansas. State Board of Education.
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