Results 71 to 80 of about 13,037,600 (316)

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Research progress on the quality of life of patients with diabetic retinopathy (糖尿病视网膜病变患者生活质量的研究进展)

中西医结合护理
Diabetic retinopathy, as an important microvascular complication of diabetes, has a high morbidity and disability rate, seriously affecting the quality of life of patients.
LI Shanshan (李珊珊), YANG Jiangying (杨剑英), WANG Luxia (王璐霞)   +2 more
doaj   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

The future of global health education: training for equity in global health

BMC Medical Education, 2016
Among academic institutions in the United States, interest in global health has grown substantially: by the number of students seeking global health opportunities at all stages of training, and by the increase in institutional partnerships and newly ...
L. Adams, C. Wagner, Cameron T. Nutt, A. Binagwaho   +3 more
semanticscholar   +1 more source

Ciências sociais e educação sanitária: a perspectiva da Seção de Pesquisa Social do Serviço Especial de Saúde Pública na década de 1950 Social sciences and health education: the perspective of the Special Public Health Service's Social Research Section in the 1950s

História, Ciências, Saúde: Manguinhos, 2010
Transcreve e comenta três artigos publicados no Boletim do Serviço Especial de Saúde Pública, no início da década de 1950, pelo sociólogo José Arthur Rios.
Nísia Trindade Lima, Marcos Chor Maio
doaj   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

Molecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla, Simone Venz, Ruslan Al‐Ali, Martin Wendlandt, Mandy Radefeldt, Elke Krüger   +5 more
wiley   +1 more source

DETERMINING FACTORS OF ORAL HEALTH: CULTURAL AND EDUCATION LEVEL

Romanian Journal of Medical and Dental Education, 2019
In literature there are very many studies highlighting the correlation between oral health and diverse social factors, including lifestyle, social and cultural environment, health organization and care as well as the health policy.
Murariu Alice, Livia Bobu, Claudiu Topoliceanu, Roxana Vasluianu, Norina Forna   +4 more
doaj  

Impact of Video-Based Health Education on Adolescents' Awareness of Frambusia at Puskesmas Tairi

Journal of Nursing Practice
Background: Frambusia, a neglected tropical disease, poses a significant health challenge in tropical regions, including Indonesia. The disease predominantly affects children and adolescents, especially in areas with poor sanitation. This study evaluates
Prima Dewi Kusumawati, Reni Nurhidayah, La Joni   +2 more
doaj   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source

Community-based interventions in hypertensive patients: a comparison of three health education strategies

BMC Public Health, 2015
BackgroundCommunity-based health education programs may be helpful in improving health outcomes in patients with chronic illnesses. This study aimed to evaluate community-based health education strategies in the management of hypertensive patients with ...
Chu-Hong Lu, Song-tao Tang, Y. Lei, Mianqiu Zhang, Wei-Quan Lin, Senhua Ding, Pei-Xi Wang   +6 more
semanticscholar   +1 more source