Results 81 to 90 of about 21,676,255 (302)

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Role of schools of public health libraries in health promotion/health education: report of a study conducted at the University of Michigan School of Public Health Library [PDF]

by Mary Townsend, Theresa Covington."The School of Public Health Library at the University of Michigan entered into an agreement in February 1982 with Raven Systems and Research, Inc.

core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Pretesting of Infographic as a Communication Tool on Pregnant Women During Covid-19 Period

Risk Management and Healthcare Policy, 2023
Ayu Khoirotul Umaroh,1 Belinda Meliana Elisabet,2 Dewi Ayu Puspitasari,2 Feniati Rahayu Aisyah,2 Sylviasari Risgiantini,2 Hadi Pratomo2 1Department of Public Health, Faculty of Health Sciences, Universitas Muhammadiyah Surakarta, Surakarta, Central Java,
Umaroh AK, Elisabet BM, Puspitasari DA, Aisyah FR, Risgiantini S, Pratomo H   +5 more
doaj  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Health education in colleges

, 1945
On cover: Issued jointly by L.W. Brooks, State Superintendent of Public Instruction, F.C. Beelman, M.D. Secretary and Executive Officer, Kansas State Board of Health.; "A companion publication to this report, called Health Education in Elementary and ...
Kansas. State Policy-Making Committee on Health Education.
core  

Impact of Health Education on Knowledge, Attitude, and Practice towards Human Papilloma Virus and its Vaccination [PDF]

Perspectives In Medical Research
Background: Despite the recommendation, the rate of Human Papilloma Virus (HPV) vaccine uptake is poor in developing countries. The possible reasons for this could be limited knowledge, poor acceptance, safety concerns, cost of the vaccine, and lack of ...
Santhosh Ramakrishna, Waseem Anjum, Veerabhadra Radhakrishna, Ravi Kudthni, Pooja Vishwanath   +4 more
doaj   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source