Results 71 to 80 of about 2,786,172 (314)
Tobacco use prevention : an important entry point for the development of health-promoting schools
, 1999 Published jointly with UNESCO and Education International (Brussels, Belgium)WHO/SCHOOL/98.5WHO/HPR/HEP/98.542 ...
World Health Organization. Health Education and Health Promotion Unit
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Mental health education for the Vancouver police department [PDF]
, 2019 Police officers continuously work with individuals who struggle with mental health issues. Concerns regarding criminalization of individuals with mental illness, ineffective use of the emergency department, and inadequate mental health training for ...
University of Lethbridge. Faculty of Health Sciences +1 more
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Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
HELP – the Health Education Library for People, India's first Consumer Health Education Resource Centre [PDF]
, 1999 Aniruddha Malpani
openalex +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Analysis of state health education laws : Arizona summary report [PDF]
State laws and regulations in health education serve as a foundation to drive school-based programs and instruction. Well-designed and well-implemented sexual health education programs have been shown to reduce student risky sexual behaviors and improve ...
core +1 more source
Application and Analysis of Non-Heritage Culture in Art Education in Colleges and Universities under the Background of Public Health Emergency [PDF]
, 2023 Wang Jia
openalex +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source