Results 61 to 70 of about 259,125 (260)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

DO WOMEN IN RURAL AREAS STILL PREFER HOMEBIRTH WITH TRADITIONAL BIRTH ATTENDANTS? A QUALITATIVE STUDY OF WOMEN IN RURAL AREA OF KUTAI KERTANEGARA EAST KALIMANTAN

Public Health of Indonesia, 2018
Background: There continues to be a gap between facility-based delivery and homebirth. This condition is influenced by various social and cultural factors, which in rural areas could affect childbirth in health facilities.
Annisa Nurrachmawati, Moh. Hakimi, Adi Utarini   +2 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

La unidad de cuidado intensivo, un lugar para quedarse solo The Intensive Care Unit, a place to be alone

Investigación y Educación en Enfermería, 2009
Objetivo: describir el significado que tiene la experiencia de estar hospitalizado en una Unidad de Cuidado Intensivo. Metodología: estudio con enfoque fenomenológico, realizado en Medellín, Colombia, entre los meses de abril y octubre de 2006. Incluyó 9
Óscar Alberto Beltrán Salazar
doaj  

The effectiveness of air-cleaning technologies against COVID-19 transmission in healthcare settings

Frontiers in Environmental Health
BackgroundThe healthcare setting is a high-transmission-risk environment for COVID-19. Attending clinicians and patients are at risk of infection if measures are not established to secure the microbial safety of the health facility.
Enembe Okokon, Enembe Okokon, Moriam Chibuzor, Chisom Ezema, Moses Bernard, Veronica Barde, Angela Oyo-Ita, Martin Meremikwu, WHO Colleagues   +8 more
doaj   +1 more source

The Lab on the River: The St. Anthony Falls Laboratory at the University of Minnesota

Open Rivers, 2017
When viewing the Minneapolis skyline, one generally doesn’t think of hydraulic research laboratories. Indeed, from the Stone Arch Bridge... the St. Anthony Falls Laboratory building looks rather nondescript.
Barbara Heitkamp
doaj   +1 more source

Laser programs facility management plan for environment, safety, and health [PDF]

, 1996
The Lawrence Livermore National Laboratory`s (LLNL) Laser Programs ES&H policy is established by the Associate Director for Laser Programs. This FMP is one component of that policy. Laser Programs personnel design, construct and operate research and development equipment located in various Livermore and Site 300 buildings.
openaire   +2 more sources

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source