Results 221 to 230 of about 118,473 (313)

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

New Jersey Health Care Facilities Financing Authority Annual Report

, 2020
New Jersey Health Care Facilities Financing Authority
core  

New Jersey Health Care Facilities Financing Authority Annual Report 2022

, 2022
New Jersey Health Care Facilities Financing Authority
core  

[Financing health].

Atencion primaria, 1998
openaire   +1 more source

A taxonomy for the financing of health for all

Bulletin of the World Health Organization
Huang, Vanessa, Obrizan, Maksym, Jardon-Pina, Juan   +2 more
openaire   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

The intersection of TB and health financing: defining needs and opportunities. [PDF]

IJTLD Open
Wells WA, Waseem S, Scheening S.
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Health financing and systems in African small and island states: Unique challenges and opportunities in achieving universal health coverage.

SSM Health Syst
McGuire F, Mohan S, Rao M, Nabyonga-Orem J, Nundoochan A, Sombie I, Kataika E, Bland S, Revill P.   +8 more
europepmc   +1 more source

Development partner influence on domestic health financing contributions in Senegal: a mixed-methods case study. [PDF]

Health Policy Plan
Federspiel F, Borghi J, Mbaye EM, Jensen HT, Martinez Alvarez M.   +4 more
europepmc   +1 more source