Results 231 to 240 of about 7,977,848 (398)

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

New Ideas to Help the Aquino Administration Achieve its Health Agenda [PDF]

open access: yes
One of the inaugural commitments made by the Philippines` new administration is the provision of quality and affordable health care for each and every Filipino. To achieve this, a strategic health agenda is needed. This Policy Note offers a few new ideas
Lavado, Rouselle F.
core  

Public health financing in Brazil (2019-2022): an analysis of the national health fund and implications for health management. [PDF]

open access: yesFront Public Health
Nunes Marinho L   +6 more
europepmc   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

The changing public/private mix in the American Health Care System [PDF]

open access: yes
This paper discusses the fundamental changes in the American health care system during the past four decades. By applying a multidimensional framework, the changing role of the state in financing, service provision, and in the regulation of the health ...
Cacace, Mirella
core  

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

open access: yesMolecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Financing of mental health in Estonia [PDF]

open access: yes, 2003
Habicht, Triin, Thetloff, Maie
core  

How health insurance affects the delivery of health care in developing countries [PDF]

open access: yes
Financial crisis is a common state of affairs in the government health sector of many developing countries, and an increasing number are considering implementing user charges and insurance programs to shift some of the financial burden for health ...
Barnum, Howard, Kutzin, Joseph
core  

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