Results 241 to 250 of about 684,204 (318)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Health financing and systems in African small and island states: Unique challenges and opportunities in achieving universal health coverage.

SSM Health Syst
McGuire F, Mohan S, Rao M, Nabyonga-Orem J, Nundoochan A, Sombie I, Kataika E, Bland S, Revill P.   +8 more
europepmc   +1 more source

Development partner influence on domestic health financing contributions in Senegal: a mixed-methods case study. [PDF]

Health Policy Plan
Federspiel F, Borghi J, Mbaye EM, Jensen HT, Martinez Alvarez M.   +4 more
europepmc   +1 more source

Renal health care: production function and financing

, 2003
Vieira, Miguel
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

The intersection of TB and health financing: defining needs and opportunities. [PDF]

IJTLD Open
Wells WA, Waseem S, Scheening S.
europepmc   +1 more source

Financing of Pediatric Home Health Care: Policy Statement [PDF]

Carolyn C. Foster, Renee M. Turchi, Elaine Lin, Amy J. Houtrow, Patrick Jones, Matthew Sadof, Edwin Simpser, John Langley, James M. Perrin, Lisa Chamberlain, Alison Galbraith, Jennifer D. Kusma, William B. Moskowitz, Jean L. Raphael, Renee M. Turchi, Renee Turchi   +15 more
openalex   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Correction: From lemming to leader: Moving beyond Gross Domestic Product (GDP) to bring health financing assistance into the 21st century. [PDF]

PLOS Glob Public Health
Nassiri-Ansari T, Schwalbe N, Lehtimaki S.   +2 more
europepmc   +1 more source