Results 131 to 140 of about 4,764,626 (316)
MachinesIndustrial health assessment often faces the challenge of sensor scarcity and a lack of labelled failure datasets, making conventional monitoring difficult to scale.
Dominik Hornacek, Pavol Tanuska
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Analytical Health Indices: Towards Reliability-Informed Deep Learning for PHM
International Journal of Prognostics and Health ManagementDeep learning has demonstrated significant potential for prognostics in complex systems (Fink et al., 2020). Recent advances in physics-informed machine learning have integrated physics-of-failure principles within data-driven models (AriasChao, Kulkarni,
Pierre Dersin +3 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Engineering ReportsAccurate and timely health status assessment of power converter systems is crucial for ensuring the reliability and safety of power equipment. Conventional health assessment methods for power converters often rely on static models or fixed‐weight Health ...
Xiaojiu Ma +3 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Review of: Amer EI-Ahraf et al., The Impact of Public Policy on Environmental Quality and Health: The Case of Land Use Management and Planning [PDF]
, 2000 Review of the book The Impact of Public Policy on Environmental Quality and Health: The Case of Land Use Management and Planning by Amer El-Ahraf et al., (Quorum Books 1999). Acknowledgments, introduction, appendixes, selected bibliography, index. ISBN 1-
Carrier, Jason J.
core +2 more sources
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source