Results 41 to 50 of about 12,072,755 (252)

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Developing competencies in health informatics: Blended teaching method

GMS Medizinische Informatik, Biometrie und Epidemiologie
The rapid development in health informatics has improved health outcomes but also poses challenges. Healthcare professionals need health information technology competencies for effective decision-making. This study aims to identify key health informatics
Mannevaara, Pauleen, Saranto, Kaija, Kinnunen, Ulla-Mari   +2 more
doaj   +1 more source

One health informatics

Proceedings of the 23rd International Conference on World Wide Web, 2014
Zoonoses are a class of infectious diseases causing growing concern of health authorities worldwide. Human and economic costs of zoonoses are substantial, especially in low-resource countries. New zoonoses emerge as a consequence of ecological, demographic, cultural, social and behavioral factors.
openaire   +3 more sources

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Online digital health and informatics education for undergraduate nursing students in China: impacts and recommendations

BMC Medical Education
Background Digital health plays a vital role in healthcare services. Governments in many countries, including China, are increasingly advocating for the appropriate use of digital technologies to address significant health system challenges.
Hongxia Shen, Chong Chen, Sijing Yan, Cynthia Hallensleben, Rianne van der Kleij, Minyi Li, Huohuo Dai, Niels Chavannes, Ying Zhou   +8 more
doaj   +1 more source

Designing and Delivering a Public Health Informatics Course

Issues in Science and Technology Librarianship, 2000
Public health is a discipline increasingly reliant on the dissemination, manipulation and synthesis of information from a variety of sources. Public health practitioners now do much of their surveillance, advocacy, reporting, data analysis, and data ...
William Olmstadt, Gale G. Hannigan
doaj   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Analyzing and Visualizing Knowledge Structures of Health Informatics from 1974 to 2018: A Bibliometric and Social Network Analysis [PDF]

Healthcare Informatics Research, 2019
ObjectivesThis paper aims to provide a theoretical clarification of the health informatics field by conducting a quantitative review analysis of the health informatics literature.
Tahereh Saheb, Mohammad Saheb
doaj   +1 more source

Understanding Further the Phenotypic Spectrum of Central Nervous System Inflammatory Demyelinating Disorders Using Unsupervised Clustering

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec, Elif Everest, Melih Tutuncu, Ugur Bilge, Sabahattin Saip, Ugur Uygunoglu, Aksel Siva   +6 more
wiley   +1 more source

Current state of digital health literacy and its association with informatics competency among nurses: a cross-sectional study [PDF]

Exploration of Digital Health Technologies
Aim: The global promotion of digital health is accelerating the transformation of healthcare systems. Consequently, in contemporary healthcare environments characterized by information overload, nurses are increasingly demanded to possess advanced ...
Lili Lei, Hideaki Furuki, Nao Sonoda, Akiko Morimoto   +3 more
doaj   +1 more source