Results 71 to 80 of about 445,340 (275)

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Medical information seeking behavior of urban patients in Zhejiang Province, China: a cross-sectional study

BMC Public Health, 2022
Background Health information seeking behavior (HISB) is a prevalent research topic. However, little is known about sociodemographic factors of HISB in China.
Liyun Liu
doaj   +1 more source

Parental digital health information seeking behavior in Switzerland: a cross-sectional study

BMC Public Health, 2019
BackgroundDigital media are increasingly abundant and used to seek health information, however, to date very little is known on parents’ seeking behavior in the context of child’s health and development outside English-speaking and Scandinavian countries.
R. Jaks, I. Baumann, S. Juvalta, J. Dratva   +3 more
semanticscholar   +1 more source

Lifestyle Segmentation to Explain the Online Health Information–Seeking Behavior of Older Adults: Representative Telephone Survey

Journal of Medical Internet Research, 2020
Background As a result of demographic changes, the number of people aged 60 years and older has been increasing steadily. Therefore, older adults have become more important as a target group for health communication efforts.
Winja Weber, Anne Reinhardt, C. Rossmann
semanticscholar   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Predictors of Mental Health Literacy and Information Seeking Behavior Toward Mental Health Among University Students in Resource-Limited Settings

International Journal of General Medicine, 2022
Binyam Tariku Seboka,1 Samuel Hailegebreal,2 Misrak Negash,3 Tizalegn Tesfaye Mamo,1 Helen Ali Ewune,1 Girma Gilano,2 Delelegn Emwodew Yehualashet,1 Gelila Gizachew,3 Abel Desalegn Demeke,4 Aynadis Worku,5 Habtamu Endashaw,1 Chalachew Kassawe,3 Endris ...
Tariku Seboka B, Hailegebreal S, Negash M, Mamo TT, Ali Ewune H, Gilano G, Yehualashet DE, Gizachew G, Demeke AD, Worku A, Endashaw H, Kassawe C, Amede ES, Kassa R, Tesfa GA   +14 more
doaj  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Design and Developing of Health Information Behavior Questionnaire [PDF]

پیاورد سلامت
Background and Aim: The term “information behavior,” with an emphasis on health and hygiene, refers to purposeful actions taken to satisfy informational needs related to health.
Shahnaz Khademizadeh, Bahram Peymannia, Fatemeh Rafieinasab   +2 more
doaj  

Digital Health Literacy and Health Information Seeking Behavior among Adolescents in Indonesia

Jurnal PROMKES
Background: The widespread use of the internet among adolescents has transformed how they access health information. However, the abundance of unverified online content poses risks for individuals who lack the skills to assess its credibility.
D. Sutha, Christine, Siti Novianti, Asri Handayani Solihin   +3 more
semanticscholar   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source