Results 101 to 110 of about 9,121,442 (394)

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

The 3LGM2-tool to support information management in health care / Der 3LGM2-Baukasten zur Unterstützung des Informationsmanagements im Gesundheitswesen

open access: yesGMS Medizinische Informatik, Biometrie und Epidemiologie, 2011
Hospital information systems (HIS) as well as transinstitutional health information systems (tHIS) are constructed like a (complex of) building(s) out of different and probably heterogeneous bricks and components.
Winter, Alfred
doaj  

The nicotinamide hypothesis revisited—plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione

open access: yesFEBS Letters, EarlyView.
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley   +1 more source

Strengthening health information systems to address health equity challenges

open access: yesBulletin of the World Health Organization, 2005
Special studies and isolated initiatives over the past several decades in low-, middle- and high-income countries have consistently shown inequalities in health among socioeconomic groups and by gender, race or ethnicity, geographical area and other ...
Lexi Bambas Nolen   +8 more
doaj  

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

Health Information Systems - Technology and Acceptance [PDF]

open access: yesYearbook of Medical Informatics, 2007
SummaryTo summarize current outstanding research in the field of health information systems (HIS).Synopsis of the articles selected for the IMIA Yearbook 2007.Five articles from three international peer reviewed journals were selected for the HIS section of the IMIA Yearbook 2007.
openaire   +3 more sources

International Profiles of Health Care Systems, 2012 [PDF]

open access: yes, 2012
This publication presents overviews of the health care systems of Australia, Canada, Denmark, England, France, Germany, Japan, Iceland, Italy, the Netherlands, New Zealand, Norway, Sweden, Switzerland, and the United States.

core  

Analyzing recommender systems for health promotion using a multidisciplinary taxonomy: A scoping review [PDF]

open access: yes, 2018
Background: Recommender systems are information retrieval systems that provide users with relevant items (e.g., through messages). Despite their extensive use in the e-commerce and leisure domains, their application in healthcare is still in its ...
Civit Balcells, Antón   +6 more
core   +1 more source

Assessing the ability of health information systems in hospitals to support evidence-informed decisions in Kenya

open access: yesGlobal Health Action, 2014
Background Hospital management information systems (HMIS) is a key component of national health information systems (HIS), and actions required of hospital management to support information generation in Kenya are articulated in specific policy documents.
E. Kihuba   +7 more
semanticscholar   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

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