Results 131 to 140 of about 1,959,318 (304)

Health information system.

Einstein (Sao Paulo, Brazil), 2013
de Souza, Valéria Pinheiro, dos Santos, Oscar Fernando Pavão, Wolosker, Nelson   +2 more
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Integrating equity into health information systems: a human rights approach to health and information. [PDF]

PLoS Medicine, 2005
Lexi Bambas
doaj   +2 more sources

Going Abroad of Korean Health Information Systems [PDF]

Healthcare Informatics Research, 2014
Young Moon Chae
doaj   +1 more source

The negative impact of the COVID-19 pandemic on breast cancer tackle in Brazil’s public and private healthcare system: time series study between 2014 and 2022

BMC Health Services Research
Background The COVID-19 pandemic has overwhelmed the healthcare systems of many countries and negatively impacted the care of other diseases. Objective To evaluate the trend of screening mammograms, oncological breast surgeries, and breast cancer ...
Adriano Hyeda, Élide Sbardellotto Mariano Costa, Sérgio Candido Kowalski   +2 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

The Role of Information Technology in Strengthening Vital Statistics in Public Health Institutions in Sana’a, Yemen

Risk Management and Healthcare Policy
Al-Safi Noman,1 Kassim Alshargabi,1,2 Sarah Noman3 1Center of Public Administration Development, Sana’a University, Sana’a, Yemen; 2Faculty of Commerce and Economics, Amran University, Amran, Yemen; 3Department of Community Health, Faculty of Medicine ...
Noman AS, Alshargabi K, Noman S
doaj  

Aligning Health Information Systems with Organizational Objectives by Chief Information Officers

مدیریت اطلاعات سلامت, 2016
Introduction: The alignment of information systems with organizational objectives is a key challenge for health care organizations and the key to the success of the organization.
Hamid Moghaddasi, Leila Ghaderi-Nansa
doaj  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source