Results 131 to 140 of about 5,124,765 (263)

Going Abroad of Korean Health Information Systems [PDF]

open access: yesHealthcare Informatics Research, 2014
Young Moon Chae
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Creating partnerships for capacity building in developing countries - the experience of the World Bank [PDF]

open access: yes
The authors discuss a variety of experiences in a number of transition, and developing countries to build institutional capacity for economics education. A flexible approach met with some success.
Bader, William   +2 more
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Aligning Health Information Systems with Organizational Objectives by Chief Information Officers

open access: yesمدیریت اطلاعات سلامت, 2016
Introduction: The alignment of information systems with organizational objectives is a key challenge for health care organizations and the key to the success of the organization.
Hamid Moghaddasi, Leila Ghaderi-Nansa
doaj  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Uptake, scale up, integration of vaccine, immunization, and health supply chain management technologies and innovation into policy: experience from Tanzania

open access: yesBMC Health Services Research
Background The uptake, scale-up, and integration of technologies and innovations have been the emphasis of the government of Tanzania for sustained health systems strengthening.
Henry A. Mollel   +2 more
doaj   +1 more source

Analysing regulatory systems in mixed public-private health systems: a new assessment tool and its application in India [PDF]

open access: yes
Health systems in many low- and middle-income countries (LMICs) in the Asia-Pacific region can be characterised as mixed public-private systems, with common features such as blurred boundaries between public and private sectors, low government ...
Krishna Hort
core  

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

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