Results 101 to 110 of about 4,258,214 (347)

INFORMATION TECHNOLOGY-BASED HEALTH CARE

open access: green, 2023
Abdullaeva Zamira Shamshaddinovna Yakubov Maksadkhon Sultaniyazovich
openalex   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

The Impact of Information Technology on Emergency Health Care Outcomes [PDF]

open access: yes
This paper analyzes the productivity of technology and job design in emergency response systems, or 911 systems.' During the 1990s, many 911 systems adopted Enhanced 911' (E911), where information technology is used to link automatic caller ...
Scott Stern, Susan Athey
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Accelerating health information technology capabilities across England's National Health Service

open access: yesThe Lancet: Digital Health, 2021
Kathrin Cresswell   +2 more
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Development in the adoption of a national digital healthcare system and experience at taking new technology in use – changes from 2019 to 2022

open access: yesInformation Research: An International Electronic Journal
Introduction. The adoption of a national digital system for healthcare services in Iceland, and how people perceive their possibilities to adopt new technology is examined. Method.
Ágústa Pálsdóttir
doaj   +3 more sources

Perspectives of Inpatients With Cirrhosis and Caregivers on Using Health Information Technology: Cross-sectional Multicenter Study [PDF]

open access: gold, 2021
Chathur Acharya   +11 more
openalex   +1 more source

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