Results 31 to 40 of about 1,607,450 (303)

Health Information Technology Usability Evaluation Scale (Health-ITUES) for Usability Assessment of Mobile Health Technology: Validation Study

JMIR mHealth and uHealth, 2018
BackgroundMobile technology has become a ubiquitous technology and can be particularly useful in the delivery of health interventions. This technology can allow us to deliver interventions to scale, cover broad geographic areas, and deliver technologies ...
Schnall, Rebecca, Cho, Hwayoung, Liu, Jianfang   +2 more
doaj   +1 more source

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi, Rie Tanaka, Reona Kawahira, Shingo Nabeta, Kouhei Naoi, Kazuhito Kitajima, Akira Wada, Tomonari Takagi, Norihiko Ohura, Akira Miyamoto   +9 more
wiley   +1 more source

Health Information Technology Acceptance Framework for diabetes management

Heliyon, 2019
This study examined the level of acceptance of Health Information Technology (HIT) as tools for diabetes care and management, in six selected tertiary hospitals in southwestern zone of Nigeria.
O.S. Ayanlade, T.O. Oyebisi, B.A. Kolawole   +2 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Systematic review and economic modelling of the relative clinical benefit and cost-effectiveness of laparoscopic surgery and robotic surgery for removal of the prostate in men with localised prostate cancer [PDF]

, 2012
PMID: 23127367 [PubMed - indexed for MEDLINE] Free full text Funding for this study was provided by the Health Technology Assessment programme of the National Institute for Health Research.Peer ...
Royle, J., C Robertson, Pickard, R., C Ramsay, Close, A, Jia, X., Fraser, C., Armstrong, N, Royle, J, Rushton, S P, Robertson, C., Ramsay, C, D Jenkinson, Gurung, T, Lam, T B, Mowatt, G, Fraser, C, Neal, D. E., Rushton, S. P., Armstrong, N., Eden, C. G., MC Robinson, Jenkinson, D, Robinson, M. C., CG Eden, Vale, L, Sharma, P., MDF Shirley, DA Barocas, Lam, T. B., Sharma, P, J Royle, Neal, D E, L Vale, Close, A., Barocas, D A, Robinson, M C, A Close, Robertson, C, TB Lam, DE Neal, Ramsay, C. R. (Craig R.), Gurung, T. (Tara), Mowatt, G., C Fraser, Shirley, M D F, SP Rushton, N Armstrong, Pickard, R, Eden, C G, Barocas, D. A., P Sharma, Vale, L. (Luke), Jenkinson, D., T Gurung, R Pickard, Soomro, N., G Mowatt, Shirley, M. D. F., Jia, X, Soomro, N, N Soomro, X Jia   +62 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

European network for Health Technology Assessment, EUnetHTA: Planning, development, and implementation of a sustainable European network for Health Technology Assessment

, 2009
Udgivelsesdato: 2009-DecOBJECTIVES: The European network on Health Technology Assessment (EUnetHTA) aimed to produce tangible and practical results to be used in the various phases of health technology assessment and to establish a framework and ...
Rehnqvist, Nina, Nielsen, Camilla Palmhoj, Haheim, Lise Lund, Morland, Berit, Lee-Robin, Sun Hae, Busse, Reinhard, Nielsen, Camilla Palmhøj, Neikter, Susanna Allgurin, Espallargues, Mireia, Wild, Claudia, Kristensen, Finn Borlum, Makela, Marjukka, Kristensen, Finn Børlum, Milne, Ruairidh, Chamova, Julia, Mørland, Berit   +15 more
core   +1 more source