Results 61 to 70 of about 4,201,714 (253)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
A Future of Failure? The Flow of Technology Talent into Government and Civil Society [PDF]
, 2013 This report is an evaluation of the technology talent landscape shows a severe paucity of individuals with technical skills in computer science, data science, and the Internet or other information technology expertise in civil society and government.
Alexander Hart, Sam Gill, Tom Freedman
core
Healthcare disparities and models for change. [PDF]
, 2004 With Healthy People 2010 making the goal of eliminating health disparities a national priority, policymakers, researchers, medical centers, managed care organizations (MCOs), and advocacy organizations have been called on to move beyond the historic ...
Baquet, Claudia R +2 more
core +2 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Evolution of the availability of Information and Communication Technologies in primary health care in Brazil, 2012 to 2018 [PDF]
Revista Brasileira de EpidemiologiaObjective: To verify the evolution of the availability of information and communication technology equipment and inputs in primary health care services that participated in the external evaluation of the Access and Quality Improvement Program in Primary ...
Janaína Duarte Bender +4 more
doaj +1 more source
Health Care Information Technology: Securing the Electronic Health Record with Biometric Technology [PDF]
, 2014 The principal focus of this paper is to examine the integration of biometric technology into healthcare’s information technology systems. Biometric technology, a rapidly evolving mechanism, analyzes specific anatomical and physiological features of an ...
Iacona, Alyssa
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Public Health of IndonesiaBackground:Health policies in Indonesia facilitate public access to healthcare information in efforts to improve public health. These policies rely on the support of electronic healthcare information systems to provide health data and information ...
Jumakil Jumakil +3 more
doaj +1 more source