Results 101 to 110 of about 7,069,482 (314)

Embodying 'health citizenship' in health knowledge to fight health inequalities [PDF]

Revista Brasileira de Enfermagem, 2011
This paper wishes to contribute to the debate around citizen participation in health system decision-making that has been present internationally for the last 30 years. I argue that if we aim to change health inequalities, health professionals and planners need to understand the illness and health service experience of citizens.
openaire   +5 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Water, Health, and Social Technologies: One Million Cisterns Programme Case Study

Annals of Global Health
Background: This paper focuses on the impacts of climate change on vulnerable ecosystems and its implications for the health and well-being of populations.
José Firmino de Sousa Filho, Walisson Angélico de Araújo, Mariana Sebastião, Adalton Fonseca, Raíza Tourinho, Denise Pimenta, Gervásio Santos, Lucas Emanuel, Roberto F. S. Andrade, Gustavo Casais, Gisele Paixão, Andrea Ferreira, Rachel Coelho, Maria Yuri Ichihara, Júlia Pescarini, Joanna M. N. Guimarães, Paulo Victor da Costa, Ismael Silveira, Rafael Silva, Rita Ribeiro, Maurício L. Barreto, On behalf of the SEDHI team   +21 more
doaj   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Knowledge management and communities of practice in the private sector: lessons for modernising the National Health Service in England and Wales [PDF]

, 2002
The National Health Service (NHS) in England and Wales has embarked upon a radical and farreaching programme of change and reform. However, to date the results of organizational quality and service improvement initiatives in the public sector have been ...
Bate, SP, Robert, G
core  

Comparative safety of anti-epileptic drugs during pregnancy: a systematic review and network meta-analysis of congenital malformations and prenatal outcomes

BMC Medicine, 2017
Background Pregnant women with epilepsy frequently experience seizures related to pregnancy complications and are often prescribed anti-epileptic drugs (AEDs) to manage their symptoms.
Areti Angeliki Veroniki, Elise Cogo, Patricia Rios, Sharon E. Straus, Yaron Finkelstein, Ryan Kealey, Emily Reynen, Charlene Soobiah, Kednapa Thavorn, Brian Hutton, Brenda R. Hemmelgarn, Fatemeh Yazdi, Jennifer D’Souza, Heather MacDonald, Andrea C. Tricco   +14 more
doaj   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Whose knowledge is of most worth? The importance of listening to the voice of the learner. [PDF]

, 2004
This paper discusses some of the data produced in the course of a research study that examined the perceptions that primary school aged children (7-13 year olds) had about their learning in health education.
Scratchley, Margaret J.
core   +1 more source

Effect of lateral positioning on ventilation in patients with blunt thoracic injury during pressure support ventilation: the VICTORY study

Intensive Care Medicine Experimental
Background In patients with blunt thoracic injury requiring mechanical ventilation lateral positioning is routinely performed. Whether it modifies ventilation distribution and aeration is unclear.
Vorakamol Phoophiboon, Antenor Rodrigues, Matthew Ko, Luca S. Menga, Fernando Vieira, Mattia Docci, Kiana Sharifi, Annia Schreiber, Mayson L. A. Sousa, Alberto Goffi, Andrea Rigamonti, Laurent Brochard   +11 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source