Results 151 to 160 of about 21,438,996 (314)
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Mirex : health and safety guide
Published by the World Health Organization for the International Programme on Chemical SafetyCompanion volume to: Environmental health criteria ; 4428 ...
World Health Organization
core
In the European Union, the escalating generation of waste, together with the difficulties in finding new places for its disposal, have led to choose for incineration as an alternative to the management of non-reusable or recyclable waste, recovering it ...
Loreto Santa-Marina +7 more
doaj
Introduction Literature has established that offering protection for workers’ health and safety is one method of preserving an organization’s human resources and increase worker productivity.
Michael Afari Baidoo +3 more
doaj +1 more source
Spatio-Temporal Comprehensive Measurements of Chinese Citizens' Health Levels and Associated Influencing Factors. [PDF]
Lu C, Jin S, Tang X, Lu C, Li H, Pang J.
europepmc +1 more source
Measuring Community Health Levels [PDF]
openaire +2 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source

