Results 151 to 160 of about 9,052,729 (313)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Resource allocation, health mobility and adaptation to illness [PDF]

The increased availability of panel data has made it possible to estimate and measure health mobility for population subgroups who may have systematically different levels of mobility.
Hauck, K., Hollingsworth, B., Tsuchiya, A.   +2 more
core  

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Examining the relationship between occupational health and safety practices and productivity levels in private health facilities in the central region of Ghana

BMC Public Health
Introduction Literature has established that offering protection for workers’ health and safety is one method of preserving an organization’s human resources and increase worker productivity.
Michael Afari Baidoo, Emmanuel Kumah, Saansong Omar Ansir Ahmed, Judith Ayormisi Fafali   +3 more
doaj   +1 more source

Health Personnel's Knowledge Level on Health Literacy

, 2016
WOS ...
Durmaz, Yasar, Yayan, E. Hilal, Sezgin, Deniz, Yakinci, Cengiz   +3 more
openaire   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Cardiac Rehabilitation on Health Behaviors and Clinical Outcomes Among Myocardial Infarction Patients [PDF]

, 2016
The lack of adherence to health behaviors in cardiac rehabilitation (CR) is the leading cause of recurrent myocardial infarction (MI) in Indonesia. This randomized control trial (RCT) study was conducted to examine the effect of a family based self ...
Herliani, Y. K. (Yusshy), Kritpracha, C. (Charuwan), Matchim, Y. (Yaowarat)   +2 more
core  

Mid-level health providers: a promising resource.

Revista peruana de medicina experimental y salud publica, 2011
Los trabajadores de salud de nivel intermedio (TSNI) son trabajadores capacitados en una institución de educación superior durante al menos dos a tres años, quienes son autorizados y regulados para trabajar de forma autónoma para el diagnóstico, control y tratamiento de dolencias, enfermedades y discapacidades, así como participar en la prevención y ...
Brown, A., Cometto, G., Cumbi, A., de Pinho, H., Kamwendo, F., Lehmann, U., McCourt, W., McPake, Barbara, Pariyo, G., Sanders, D.   +9 more
openaire   +4 more sources