Results 161 to 170 of about 9,052,729 (313)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Evaluation of the factors affecting the health literacy levels of patients admitted to family health centers

Family Medicine & Primary Care Review, 2021
Özgül Örsal, Pınar Duru, Özlem Örsal, Kazım Tırpan, Abdullah Çulhacı   +4 more
doaj   +1 more source

Health Level Seven [PDF]

, 2020
openaire   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Approach for assessing the influence of an Energy Recovery plant: A case study in Gipuzkoa (Basque Country, Spain)

Revista de Salud Ambiental
In the European Union, the escalating generation of waste, together with the difficulties in finding new places for its disposal, have led to choose for incineration as an alternative to the management of non-reusable or recyclable waste, recovering it ...
Loreto Santa-Marina, Amaia Irizar, Aitana Lertxundi, Nerea Urbieta, Ziortza Barroeta, Alba Jimeno-Romero, Miren Begoña Zubero, Jesus Ibarluzea   +7 more
doaj  

Spatio-Temporal Comprehensive Measurements of Chinese Citizens' Health Levels and Associated Influencing Factors. [PDF]

Healthcare (Basel), 2020
Lu C, Jin S, Tang X, Lu C, Li H, Pang J.
europepmc   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Have COVID-19-Related Economic Shocks Affected the Health Levels of Individuals in the United States and the United Kingdom? [PDF]

Front Public Health, 2020
Jiang B, Liu Z, Shen R, Huang L, Tong Y, Xia Y.   +5 more
europepmc   +1 more source

Levels of Health [PDF]

Nature, 1958
openaire   +1 more source