Results 41 to 50 of about 3,591,872 (263)

Nuclear import of PTPN18 inhibits breast cancer metastasis mediated by MVP and importin β2

Cell Death and Disease, 2022
Distant metastasis is the primary cause of breast cancer-associated death. The existing information, such as the precise molecular mechanisms and effective therapeutic strategies targeting metastasis, is insufficient to combat breast cancer.
Tao Wang, Xinlei Ba, Xiaonan Zhang, Na Zhang, Guowen Wang, Bin Bai, Tong Li, Jiahui Zhao, Yanjiao Zhao, Yang Yu, Bing Wang   +10 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Clinical guideline for postoperative nutrition support in neonates with enterostomy (2024)

Pediatric Investigation
This is an evidence‐based guideline for postoperative nutritional management of neonates with enterostomy. There were 10 clinical questions in enteral nutrition management, parenteral nutrition management, and post‐discharge follow‐up (including the ...
Beijing Children's Hospital, Capital Medical University, National Center for Children's Health | Editorial Board of Chinese Journal of Neonatology | Life Support Group in Neonatologist Subdivision of Chinese Medical Doctor Association
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Spiritual Health and Pure Life

پژوهش در دین و سلامت, 2016
For downloading the full-text of this article please click here. Spiritual health, as one of the aspects of health, has recently been considered by Western researcher and led them to mention some definitions for it.
Mohammad Ali Heidarnia
doaj  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Benchmarks and methods for 3D medical image retrieval

Scientific Reports
The increasing use of medical imaging in healthcare settings presents a significant challenge due to the additional workload for radiologists, yet it also offers opportunity for enhancing healthcare outcomes if effectively leveraged.
Asma Ben Abacha, Alberto Santamaría-Pang, Ho Hin Lee, Jameson Merkow, Qin Cai, Surya Teja Devarakonda, Abdullah Islam, Julia Gong, Matthew Lungren, Reza Forghani, Ankush Jindal, Thomas Lin, Noel C. F. Codella, Ivan Tarapov   +13 more
doaj   +1 more source

The advantages of Structural Equation Modelling to address the complexity of spatial reference learning

Frontiers in Behavioral Neuroscience, 2016
Background: Cognitive performance is a complex process influenced by multiple factors. Cognitive assessment in experimental animals is often based on longitudinal datasets analyzed using uni- and multivariate analyses that do not account for the temporal
Pedro Silva Moreira, Ioannis eSotiropoulos, Joana eSilva, Akihiko eTakashima, Nuno eSousa, Hugo eLeite-Almeida, Patrício Soares Costa   +6 more
doaj   +1 more source