Results 61 to 70 of about 3,591,872 (263)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

The acceptability of screening for Carbapenemase Producing Enterobacteriaceae (CPE): cross-sectional survey of nursing staff and the general publics’ perceptions

Antimicrobial Resistance and Infection Control, 2018
Background Carbapenemase Producing Enterobacteriaceae (CPE) has spread rapidly and presents a growing challenge in antimicrobial resistance (AMR) management internationally. Screening for CPE may involve a rectal swab, there are limited treatment options
Kay Currie, Caroline King, Kareena McAloney-Kocaman, Nicola J. Roberts, Jennifer MacDonald, Adele Dickson, Shona Cairns, Nitish Khanna, Paul Flowers, Jacqui Reilly, Lesley Price   +10 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Health-related quality of life in dialysis patients with constipation: a cross-sectional study

Patient Preference and Adherence, 2013
JiSheng Zhang,1,* CongYang Huang,1,* YanLi Li,1 Jun Chen,2 FangYuan Shen,1 Qiang Yao,3 JiaQi Qian,4 BeiYan Bao,1 XuPing Yao51Division of Nephrology, School of Medicine, Ningbo Urology and Nephrology Hospital, Ningbo University, Ningbo, Zhejiang, People ...
Zhang JS, Huang CY, Li YL, Chen J, Shen FY, Yao Q, Qian JQ, Bao BY, Yao XP   +8 more
doaj  

Time-series transcriptomic analysis of Nile tilapia reveals the crucial roles of long non-coding RNA and transcription factor in response to Aeromonas veronii infection

BMC Genomics
Nile tilapia (Oreochromis niloticus) is a vital aquaculture species worldwide, prized for its rapid growth and high productivity. However, the increasing prevalence of Aeromonas veronii infections has led to significant economic losses in the Nile ...
Zhenzhang Lu, Anyi Li, Qianglong Sheng, Xiang Ma, Yanqiong Tang, Juanjuan Li, Xue Chi, Zhu Liu, Hong Li   +8 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Irrational parenthood cognitions and health-related quality of life among infertile women

International Journal of General Medicine, 2012
Zahra Fardiazar,1 Louiz Amanati,2 Saber Azami31Women’s Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran; 2Faculty of Medicine, Hacttepe University, Ankara, Turkey; 3Injury Epidemiology and Prevention ...
Fardiazar Z, Amanati L, Azami S
doaj  

Identification of a lipid oxygen radical defense pathway and its epigenetic control

Nature Communications
Membrane phospholipids are vulnerable to oxidative radicals, and uncontrolled lipid peroxidation affects cell viability. Cells have evolved quality control and defense mechanisms, of which the genetic regulation is not fully understood. Here, we identify
Francisco S. Mesquita, Laurence Abrami, Romain Forey, Béatrice Kunz, Charlène Raclot, Lucie Bracq, Filipe Martins, Danica Milovanovic, Evarist Planet, Olga Rosspopoff, Didier Trono, F. Gisou van der Goot   +11 more
doaj   +1 more source

Life course epidemiology and public health

The Lancet Public Health
Summary: Life course epidemiology aims to study the effect of exposures on health outcomes across the life course from a social, behavioural, and biological perspective.
Cornelia Wagner, MSc, Cristian Carmeli, PhD, Josephine Jackisch, PhD, Mika Kivimäki, ProfPhD, Bernadette W A van der Linden, PhD, Stéphane Cullati, PhD, Arnaud Chiolero, ProfMD PhD   +6 more
doaj   +1 more source