Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Medical Malpractice and Health Maintenance Organizations: Evolving Theories and ERISA\u27s Impact [PDF]
Employers are now turning in increasing numbers to Health Maintenance Organizations ( HMO ) and Preferred Provider Organizations ( PPO ) to deliver health insurance benefits to their ...
Zamora, O. Mark
core +1 more source
The response of the private sector to competitive contracting: a case study of a private health provider network in Thailand. [PDF]
Social health . lnsurance in developed countries , lS facing problems concerning cost control. In developing countries, problems are of low coverage, the provision of care to include access to the private sector, equity in access to services, as ...
Siriwanarngsun, Porntep
core +1 more source
Background: Within Canada, internet-delivered cognitive behavioural therapy (ICBT) has recently been tailored by PSPNET to meet the needs of public safety personnel (PSP) to help address high rates of mental health problems within this population ...
Janine D. Beahm +4 more
doaj +1 more source
Observing Privilege: Examining Race, Class, and Gender in Health and Human Service Organizations
Race, class, and gender dynamics can result in power differentials and discrimination in organizations. Such deleterious effects are particularly troubling for non-profit agencies with diverse employee and community bases and that ...
Leslie Collins, Sandra L. Barnes
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Stakeholders responses on health maintenance organizations participation in Nigeria’s national health insurance scheme [PDF]
National Health Insurance Scheme uses the services of Health Maintenance Organizations to run the scheme. This model of administering a national health insurance scheme is different from how so many other national health insurance programs are run in ...
Emmanuel, Emelda I.
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Detailed description of the effect Health Maintenance Organizations\u27 bad reputat [PDF]
Detailed description of the effect Health Maintenance Organizations\u27 bad reputation has on Community Health ...
Hyde, Christopher
core
Background Website evaluation is a key issue for researchers, organizations, and others responsible for designing, maintaining, endorsing, approving, and/or assessing the use and impact of interventions designed to influence health and health services ...
O’Grady, Laura +5 more
doaj +1 more source

