Results 41 to 50 of about 752,554 (285)
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Managed Care Discounting: Evidence from the MarketScan Database
Inquiry: The Journal of Health Care Organization, Provision, and Financing, 2004 The paper examines price discounting by health maintenance organizations (HMOs) and preferred provider organizations (PPOs) in markets for hospital services.
Avi Dor +2 more
doaj +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
A new scope and a vision for record linkage studies
Epidemiology, Biostatistics and Public Health, 2013 Record linkage - i.e. the use and linkage of electronic, mainly administrative databases - has been utilizedin epidemiologic research for over three decades now, starting from the system implemented in a fewUS health maintenance organizations (HMO, i.e ...
Giovanni Corrao, Carlo La Vecchia
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Too Good to be True?: The Opportunity and Cost of the $1 Building [PDF]
, 2015 A study commissioned by The Kresge Foundation's Arts & Culture Program finds that arts organizations have experienced a wide range of outcomes when acquiring low-cost or free buildings, also known as "$1 buildings." In many cases, the actual costs of ...
Kate Burgin +2 more
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Health Information Avoidance Behavior of Patients with Type 2 Diabetes Mellitus [PDF]
Journal of Library and Information Studies, 2019 Along with the convenience of receiving health information and the rise of public health consciousness, seeking health information is regarded as a common phenomenon. However, the public is seldom aware of health information avoidance behavior.
Wen-Han Chuang, Ming-Hsin Phoebe Chiu
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source