Results 51 to 60 of about 134,023 (290)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Software Maintenance and Organizational Health and Fitness [PDF]

, 2003
This chapter sets out a foundation for the management of software maintenance. The foundation highlights a fundamental for managing software maintenance effectively—recognition of the connection between managing change in organizations and the ...
Ned Chapin
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

A value-centric decision making framework for maintenance services outsourcing [PDF]

, 2011
The shift in mindset of decision makers, from maintenance being a “necessary evil” and “cost centre” to a “profit contributor” in manufacturing companies has driven outsourced maintenance suppliers to employ value-centric approaches in order to design
Toossi, Amir
core  

Factors affecting uptake of private health insurance in the Philippines

Discover Health Systems
Background As the Philippines transitions to universal health coverage, private health insurance (PHI) may contribute to bridging the health financing gap. However, only 13.0% of the country’s total health expenditure is attributed to PHI and information
Excellces Dee Montemayor, Patricia Anne P. Chua, Leivanne S. Delos Santos, Danica Isabel S. Perez, Regina Louise A. Bumatay, Jonas Francis D. Kosca, Gianella Bianca C. Samonte, Veincent Christian F. Pepito   +7 more
doaj   +1 more source

The Effect of Managed Care on Hospitals' Provision of Uncompensated Care

Inquiry: The Journal of Health Care Organization, Provision, and Financing, 2007
This study examines the effect of managed care on hospitals' provision of uncompensated care, using a new measure of managed care that is hospital-specific, rather than measured for the area as a whole, and which includes payment by preferred provider ...
Niccie L. McKay, Xiaoxian Meng
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Insurers' Competitive Strategy and Enrollment in Newly Offered Preferred Provider Organizations (PPOs)

Inquiry: The Journal of Health Care Organization, Provision, and Financing, 2007
While early growth in preferred provider organizations (PPOs) coincided with growth of managed care generally, recent expansion has come primarily at the expense of other managed care plans.
Richard A. Hirth, Kyle L. Grazier, Michael E. Chernew, Edward N. Okeke   +3 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source