Results 131 to 140 of about 1,861,055 (314)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Teaching AI to Decode Vaccine Hesitancy Narratives: A Few-Shot Learning and Topic Modeling Approach

Big Data and Cognitive Computing
Vaccine hesitancy—which can be defined as a delay in acceptance or the refusal to get vaccinated—has substantially increased over the past decade. This study introduces a computational and qualitative approach designed to efficiently classify stance and ...
Md Enamul Kabir, Shakhawat H. Tanim, Deanna D. Sellnow, Geneva Lei P. Luteria, Lior Rennert   +4 more
doaj   +1 more source

Social Networks' Engagement During the COVID-19 Pandemic in Spain: Health Media vs. Healthcare Professionals. [PDF]

Int J Environ Res Public Health, 2020
Pérez-Escoda A, Jiménez-Narros C, Perlado-Lamo-de-Espinosa M, Pedrero-Esteban LM.   +3 more
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Social media use, risk behavior engagement, and mental health among middle adolescents in the Caribbean

Background: Social media plays a pivotal role in adolescents’ lives. Social media encounters, including online risk behaviors, may influence real-world risk behaviors and mental health.
Magane, Riley, Deveaux, Lynette, Adderley, Richard, Kuang, Julia, Wang, Ava, Kim, Deogwoon, Poitier, Maxwell   +6 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

The Impact of Chatbots on Adolescent Mental Health Development: A Comprehensive Literature Review

Journal of Multidisciplinary Healthcare
Yidong Wu,1,* Tong Wu,2,* Kerun Zhu,3 Xinyu Liu,3 Jiarui Liu,3 Yuyan Wang,3 Ruojin Shi,3 Jia Xiong,3 Xinyue Xing,3 Yao Lv,3 Yaohong Niu,3 Min Peng,4 Xingyan Du1 1School of Journalism and Communication, Lanzhou University, Lanzhou, 730000,
Wu Y, Wu T, Zhu K, Liu X, Liu J, Wang Y, Shi R, Xiong J, Xing X, Lv Y, Niu Y, Peng M, Du X   +12 more
doaj  

Can health information through mobile phones close the divide in health behaviours among the marginalised? An equity analysis of Kilkari in Madhya Pradesh, India

BMJ Global Health, 2021
Amnesty Elizabeth LeFevre, Kerry Scott, Neha Shah, Jean Juste Harrisson Bashingwa, Diwakar Mohan, Sara Chamberlain, Osama Ummer, Arpita Chakraborty, Priyanka Dutt, Anna Godfrey   +9 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Health and media: an overview [PDF]

Sociology of Health & Illness, 2003
openaire   +2 more sources