Results 161 to 170 of about 1,861,055 (314)

Canadian Muslim immigrants and Western mainstream media [PDF]

open access: yes, 2019
This study sought to discover how Canadian Muslim immigrants perceive Western mainstream media’s representations of Muslims, and how they felt it affected their social integration.
University of Lethbridge. Faculty of Health Sciences   +1 more
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Social Media, Sexuality and Sexual Health Advocacy in Kolkata, India

open access: yes, 2017
This study explores emerging digital platforms in India and examines the challenges and opportunities of using these platforms for sexual health advocacy amongst gay men, other MSM and trans* women in Kolkata.
Dasgupta, Rohit, Dhall, Pawan
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Media Analysis and Public Health: Contemporary Issues in Critical Public Health

open access: yes, 2019
This volume showcases new approaches to studying public health in traditional and emerging media, suggesting that we need more analyses that focus on the production of media and on power dynamics, as well as studies of audience reception of media ...

core  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Listening for change : 2011 National Conference on Health Marketing, Communication, and Media

open access: yes
We are excited to welcome you to the 5th annual National Conference on Health Communication, Marketing, and Media. During the next 3 days, we will explore the latest health communication innovations, tools, research, and strategies.

core  

'Real men don't diet': an analysis of contemporary newspaper representations of men, food and health

open access: yes, 2007
Little research to date has focused on the meanings men attach to food and the relationship between diet and health. This is an important topic in light of the current ‘crisis’ in men's health and the role of lifestyle factors such as diet in illness ...
Gough, B
core  

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