Results 121 to 130 of about 19,379,531 (263)

Community Health Needs Assessment Data and Community Recovery From COVID-19. [PDF]

Am J Prev Med, 2022
Molella RG, Murad AL, Sherden M, Fritz DJ, Sadecki EN, Briggs G, Wang Z, Murad MH.   +7 more
europepmc   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Health impact assessment needs in south-east Asian countries

Bulletin of the World Health Organization, 2003
A situation analysis was undertaken to assess impediments to health impact assessment (HIA) in the South-East Asia Region of WHO (SEARO). The countries of the region were assessed on the policy framework and procedures for HIA, existing infrastructure ...
Caussy Deoraj, Kumar Priti, Than Sein U.
doaj  

Point-Of-Care Ultra-Sound (POCUS) for suspected surgical abdominal conditions in rural India-a mixed-method health needs assessment. [PDF]

PLOS Glob Public Health, 2023
Thomas O, Aruparayil N, Gnanaraj J, Mathew G, Nagarajan K, Shinkins B, Jayne D.   +6 more
europepmc   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Congregational health needs by key demographic variables: Findings from a congregational health needs assessment tool. [PDF]

Eval Program Plann, 2022
Harmon BE, San Diego ERN, Pichon LC, Powell TW, Rugless F, West NT, Minor L, McNeal S, McCann L, Hales LS, Davis R, Lewis J.   +11 more
europepmc   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Men's health needs assessment in the Toledo District of Southern Belize. [PDF]

BMC Public Health
Rovers J, Nicasio M.
europepmc   +1 more source

Understanding the life experiences of people with multiple complex needs: peer research in a health needs assessment. [PDF]

Eur J Public Health, 2022
Harland JM, Adams EA, Boobis S, Cheetham M, Wiseman A, Ramsay SE.   +5 more
europepmc   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source