Results 201 to 210 of about 19,379,531 (263)
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
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Assessing women's health needs
Medical Journal of Australia, 1988It has been argued that women have specific health needs aside from those of the community as a whole. As a consequence, a move towards increased "earmarked" funding for women's health has occurred. However, some debate exists about the areas of women's health that are most in need of additional funding and about appropriate mechanisms to determine ...
S, Redman +3 more
openaire +2 more sources
2020
Abstract HNA (health needs assessment) is a systematic method of identifying the unmet health and healthcare needs of a population and recommending changes to meet these unmet needs. It is used to improve health and other service planning, priority setting, and policy development.
Andrew O’Shaughnessy +2 more
openaire +1 more source
Abstract HNA (health needs assessment) is a systematic method of identifying the unmet health and healthcare needs of a population and recommending changes to meet these unmet needs. It is used to improve health and other service planning, priority setting, and policy development.
Andrew O’Shaughnessy +2 more
openaire +1 more source
2013
AbstractThis chapter will describe why health needs assessment (HNA) is important and what it means in practice. Professional training and clinical experience teaches that a health professional must systematically assess a patient before administering any treatment that is believed to be effective.
John Wright, Ben Cave
openaire +1 more source
AbstractThis chapter will describe why health needs assessment (HNA) is important and what it means in practice. Professional training and clinical experience teaches that a health professional must systematically assess a patient before administering any treatment that is believed to be effective.
John Wright, Ben Cave
openaire +1 more source
2014
Health needs assessment is conducted at many different levels: internationally, through the work of the World Health Organisation, for instance; nationally, by government health departments; and locally, from hospitals, primary care and local authority organisations right down to neighbourhood groups.
openaire +1 more source
Health needs assessment is conducted at many different levels: internationally, through the work of the World Health Organisation, for instance; nationally, by government health departments; and locally, from hospitals, primary care and local authority organisations right down to neighbourhood groups.
openaire +1 more source
The assessment of need for mental health services
Social Psychiatry and Psychiatric Epidemiology, 2005The field of psychiatric epidemiology has yielded several large and important studies of the prevalence of psychiatric disorders. These surveys have been enhanced by the inclusion of methodologies that reflect the needs for care of the population in question.
John, Joska, Alan J, Flisher
openaire +2 more sources