Results 71 to 80 of about 7,388,847 (418)

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

A cellular system to study responses to a collision between the transcription complex and a protein‐bound nick in the DNA template

FEBS Letters, EarlyView.
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring, Morten Roedgaard, Camilla Myrup Holst, Helene Christensen, Birgitta R. Knudsen, Lotte Bjergbaek, Anni Hangaard Andersen   +6 more
wiley   +1 more source

Occupational therapy: The key to unlocking locked-up occupations during the COVID-19 pandemic [version 1; peer review: 1 approved, 2 approved with reservations]

Wellcome Open Research, 2020
Occupations refer to the everyday activities that people do as individuals, in families and with communities to occupy time and bring meaning and purpose to life. It is not always limited to just paid employment. Occupations of the global population have
Sureshkumar Kamalakannan, Stuti Chakraborty   +1 more
doaj   +1 more source

Teacher Mental Health During the COVID-19 Pandemic: Informing Policies to Support Teacher Well-being and Effective Teaching Practices [PDF]

arXiv, 2021
While there is an emergence of research investigating the educational impacts of the COVID-19 pandemic, empirical studies assessing teacher mental health throughout the pandemic have been scarce. Using a large national dataset, the current study first compared mental health outcomes during the pandemic between pK-12 teachers and professionals in other ...
arxiv  

Musculoskeletal health and work ability in physically demanding occupations: study protocol for a prospective field study on construction and health care workers

BMC Public Health, 2014
BackgroundMusculoskeletal disorders have a profound impact on individual health, sickness absence and early retirement, particularly in physically demanding occupations. Demographics are changing in the developed countries, towards increasing proportions
Lars-Kristian Lunde, Markus Koch, S. Knardahl, M. Wærsted, S. Mathiassen, M. Forsman, A. Holtermann, K. B. Veiersted   +7 more
semanticscholar   +1 more source

The Development of a Rating Scale for Assessing Teaching Competencies of Health Occupations Educators in the State of Louisiana. [PDF]

, 1981
The development of a rating scale suitable for assessing teaching competencies of health occupations educators in the State of Louisiana was accomplished by: the development and validation of a questionnaire composed of 155 competency statements within ...
Casente, Constance Lirette
core   +2 more sources

Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation

Molecular Oncology, Volume 19, Issue 5, Page 1371-1385, May 2025.
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa, Zdenka Herudkova, Jan Hyl, Jakub Vlazny, Filip Sokol, Kvetoslava Matulova, Adam Folta, Jakub Hynst, Lucy Vojtova, Leos Kren, Martin Repko, Zdenek Racil, Jiri Mayer, Martin Culen   +13 more
wiley   +1 more source

Identifying Hazardous Points in Foundry Industry Using a Hybrid Safety Approach

Archives of Occupational Health, 2019
Background: In recent years, the foundry industry has had a significant impact on Iran's economy. However, the health and safety conditions of this industry are in an unfavorable status, and these conditions have caused a lot of accidents.
Omran Ahmadi, Seyed Ehsan Samaei, Maryam Farokhzad, Yahya Rasoulzadeh   +3 more
doaj  

Physically demanding occupations among females and sex-related differences to develop osteoarthritis of the hip: a systematic review and meta-analysis

Journal of Occupational Medicine and Toxicology
Background Hip osteoarthritis (HOA) is a leading cause of disability increasing with age and is more prevalent in women and in various physically demanding occupations.
Susanne Unverzagt, Annekatrin Bergmann, Kathleen Denny, Thomas Frese, Selamawit Hirpa, Johannes Weyer   +5 more
doaj   +1 more source

The Potential Impact of AI Innovations on U.S. Occupations [PDF]

arXiv, 2023
An occupation is comprised of interconnected tasks, and it is these tasks, not occupations themselves, that are affected by AI. To evaluate how tasks may be impacted, previous approaches utilized manual annotations or coarse-grained matching. Leveraging recent advancements in machine learning, we replace coarse-grained matching with more precise deep ...
arxiv