Results 111 to 120 of about 180,308,378 (306)
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Estudo longitudinal dos aspectos multidimensionais da saúde de idosos institucionalizados
Revista Brasileira de Geriatria e GerontologiaOBJETIVO: Analisar a evolução de aspectos multidimensionais da saúde de idosos institucionalizados no município de Goiânia no seguimento de dois anos. MÉTODOS: Foi realizado estudo clínico observacional longitudinal prospectivo.
Ruth Losada de Menezes +3 more
doaj +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
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, 1989 ita In Quaderni di Sanità Pubblica. - Anno 14, no. 70 (aprile 1991)jap published by: Tokyo : Japan Public Health Associationvie published by: Paris : Fondation Danielle Mitterand98 p.An expert review of recent advances in knowledge about the biology of ...
World Health Organization +1 more
core
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Voluntary-statutory partnership in community care of the elderly
, 1993 The National Council for the Elderly was established in January 1990 in succession to the National Council for the Aged which began in June ...
Mulvihill, Ray
core
Mental health of the elderly with mild cognitive impairment
, 2004 Aim: Exploring mental health of the elderly with MCI. Methods: 23 MCI subjects and 71 aged control were tested with Mental Health Inventory for Chinese Elderly, MMSE, ADL, GDS, and CMS.
C. H. Jing, B. X. Han
core +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source