Results 161 to 170 of about 180,308,378 (306)

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Use of Medicines by Community Dwelling Elderly in Ontario [PDF]

open access: yes
OBJECTIVE: Prescription medicine use by the elderly is of growing concern as indicated by a large literature focused on rising costs, patient compliance and the appropriateness of use.
Peri J. Ballantyne   +3 more
core  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Annual report of the Commissioner of Health to the Governor of Virginia.

open access: yes
Report for 1910 is found in the collected documents for 1910.Title varies slightly.Report covers fiscal year.Mode of access: Internet.Continued by: Virginia. Dept. of Health.
Virginia. Dept. of Health.
core  

Association between exposure to green and blue spaces and respiratory health in the elderly: a scoping review. [PDF]

open access: yesBMC Public Health
Lombardi GS   +5 more
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Ohio Department of Health frequently asked questions on bioterrorism

open access: yes, 2001
Electronic data (1 file; 35,082 bytes).; Title from title screen.; "Released October 13, 2001."; Text (PDF).; Overview of questions about the possibility of and actions to be taken in the event of a bioterrorist attack.; Harvested from the web on 3/7 ...
Ohio.Dept. of Health.
core  

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