Results 111 to 120 of about 8,721,191 (384)

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

open access: yesFEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado   +4 more
wiley   +1 more source

A Hybrid Approach for Fusing Physics and Data for Failure Prediction

open access: yesInternational Journal of Prognostics and Health Management, 2016
This work describes the architecture for developing physics of failure models, derived as a function of machine sensor data, and integrating with data pertaining to other relevant factors like geography, manufacturing, environment, customer and ...
Prashanth Pillai   +4 more
doaj   +1 more source

[Physical activity, health and health economics].

open access: yesTidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1980
Ideally this article should begin with a mathematical model--an equation. On the left we should put together contributions and expenditures in terms of hours, money and effort. On the right we should enter the profits in terms of years of life, money and quality of life. Unfortunately it is not that easy.
Waaler, Hans Thomas   +1 more
openaire   +3 more sources

Berberine–cinnamic acid co‐crystal effect in ameliorating hyperlipidemia might be regulated through the PI3K/AKT/mTOR/SREBP‐1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao   +7 more
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Health Physics Department. Annual progress report 1 Januar - 31 December 1983 [PDF]

open access: yes, 1978
Research in the Physics Department at Risø covers three main fields:Solid-state physicsPlasma physicsMeteorologyThe principal activities in these fields are presented in this report that covers the period from 1 January to 31 December 1978. Introductions
Risø National Laboratory, Roskilde
core   +11 more sources

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