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In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Mortality and immortality : the Nobel Prize as an experiment into the effect of status upon longevity [PDF]
It has been known for centuries that the rich and famous have longer lives than the poor and ordinary. Causality, however, remains trenchantly debated. The ideal experiment would be one in which extra status could somehow be dropped upon a sub-sample of
Adams+54 more
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A stepwise emergence of evolution in the RNA world
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro+2 more
wiley +1 more source
Summary: Osteoporosis is a prevalent condition among the elderly, and current treatments are limited by their side effects. This study aimed to develop a safe nanocarbon material with anti-osteoporotic properties.
Talante Juma+15 more
doaj +1 more source
Taras Krokhmalskii's 60th birthday [PDF]
Taras Krokhmalskii, a senior research fellow of the Institute for Condensed Matter Physics of the National Academy of Sciences of Ukraine (ICMP), a renowned specialist in the field of condensed matter physics celebrated his sixtieth birthday on February ...
Editorial Board
doaj
Editorial on New Challenges in Solar Radiation, Modeling and Remote Sensing
Accurate estimations or measurements of solar radiation are frequently required in many activities and studies in areas such as climatology, atmospheric physics and chemistry, energy and environment, ecosystems, and human health [...]
Jesús Polo, Dimitris Kaskaoutis
doaj +1 more source
Evolutionary interplay between viruses and R‐loops
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi+4 more
wiley +1 more source
When considering performing an Introductory Physics for Life Sciences course transformation for one’s own institution, life science majors’ achievement goals are a necessary consideration to ensure the pedagogical transformation will be effective ...
Andrew J. Mason, Charles A. Bertram
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Experiences with Teaching Nuclear Security Professional Development Courses for Health Physicists
Health physicists are professionals that are experts in the recognition, evaluation, and control of health hazards to permit the safe use and application of radiation. They typically have broad knowledge in radiation (ionizing and non-ionizing), biology,
Edward Waller+2 more
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