Results 81 to 90 of about 776,447 (351)

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

Understanding Health and Disease with Multidimensional Single-Cell Methods

open access: yes, 2013
Current efforts in the biomedical sciences and related interdisciplinary fields are focused on gaining a molecular understanding of health and disease, which is a problem of daunting complexity that spans many orders of magnitude in characteristic length
Banavar, Jayanth R.   +2 more
core   +1 more source

THE 65th ANNIVERSARY OF PROFESSOR IHOR STASYUK

open access: yesCondensed Matter Physics, 2003
Editorial Board of the "Condensed Matter Physics" and colleagues from the Institute for Condensed Matter Physics congratulate Professor Ihor Stasyuk on his 65th birthday and wish him to stay in good health and many more years of fruitful scientific work.
Editors
doaj  

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

open access: yesFEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi   +2 more
wiley   +1 more source

Attempt of modelling the Technnological Acceleration [PDF]

open access: yes
In this paper, we study the technological acceleration whithin a new frame work wich extends models used in the literature. The objective of our research is then to construct a global model of evaluation of the technological acceleration by two methods ...
Ajeddi, Majid
core   +1 more source

Public health in the twenty-first century: the role of advanced technologies [PDF]

open access: yes, 2014
Nearly a century ago, Charles-Edward Amory Winslow, defined public health as “the science and art of preventing disease, prolonging life, and promoting health and efficiency through organized community effort” (1).
Ramamoorthy, Venkataraghavan   +3 more
core   +2 more sources

Protocol for the operation of a breathing and vaping biomimetic robot to delineate real-time inhaled particle profile of electronic cigarettes

open access: yesSTAR Protocols, 2022
Summary: We recently developed a robotic human vaping mimetic real-time particle analyzer (HUMITIPAA) to evaluate the impact of change in chemical constituents and breathing profiles of electronic cigarettes (ECs) on potential pulmonary toxicity.
Rachel F. Bogdanoff   +2 more
doaj  

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

An Underappreciated Radiation Hazard from High Voltage Electrodes in Vacuum

open access: yes, 2016
The use of high voltage (HV) electrodes in vacuum is commonplace in physics laboratories. In such systems, it has long been known that electron emission from an HV cathode can lead to bremsstrahlung X-rays; indeed, this is the basic principle behind the ...
DeMille, David   +8 more
core  

Home - About - Disclaimer - Privacy