Results 151 to 160 of about 280,483 (314)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Central Northern Adelaide Health Service: A Social Health Atlas [PDF]

, 2005
Copyright © 2005 State of South AustraliaThe purpose of this Social Health Atlas is to provide the basis for the region to understand and determine priorities for regional health planning, and for key partners in other government or non-goverment ...
Hetzel, D., Glover, J., Anthea Page, Brombal, K., Hutchison, A., Lucinda Glover, John Glover, Glover, L., Diana Hetzel, Kristin Leahy   +9 more
core  

Carga de cáncer del departamento de Nariño y subregiones, Colombia, 2010

Revista Facultad Nacional de Salud Pública, 2014
Resumen Objetivo: medir la carga de cáncer a partir del indicador Años de Vida Saludables Perdidos (avisa) en el Departamento de Nariño y subregiones.
Elizabeth Trujillo-Montalvo, Carlos Hidalgo-Patiño, Ángela Hidalgo-Eraso, Anderson Rocha-Buelvas   +3 more
doaj  

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Health priorities. [PDF]

British medical journal, 1967
openaire   +3 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Health needs assessment in the contemporary NHS [PDF]

, 1995
Working for Patients, published in January 1989 and the subsequent NHS and Community Care Act 1990, Introduced the most major and complex reorganisation of the NHS since its inception.
Crowe, Patricia Ann
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Perceived Healthcare Priorities, Barriers, and Preferences When Selecting Private or Governmental Healthcare Services Among a Sample of University Affiliates from Saudi Arabia

Patient Preference and Adherence
Ibrahim M Gosadi, Mohammad A Jareebi Department of Family and Community Medicine, Faculty of Medicine, Jazan University, Jazan, Saudi ArabiaCorrespondence: Ibrahim M Gosadi, Department of Family and Community Medicine, Faculty of Medicine, Jazan ...
Gosadi IM, Jareebi MA
doaj