Results 251 to 260 of about 1,128,412 (358)

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Priorities in Health

, 2006
Jamison, D, Breman, J, Measham, A, Alleyne, A, Claeson, M, Evans, D, Jha, P, Mills, A, Musgrove, P   +8 more
openaire   +3 more sources

137:oral Taking a chance on health: the lottery principle, healthcare resource allocation, and orphan drugs

BMJ Global Health, 2022
Lars Sandman, Erik Gustavsson, Ken Bond
doaj   +1 more source

Incorporating individually defined brain health priorities in clinical trial outcomes: the electronic Person-Specific Outcome Measure approach in the United States. [PDF]

Alzheimers Dement (N Y)
Saunders S, Jannati A, Sheehan S, Toro-Serey C, Tobyne S, McManus K, Bates D, Showalter J, Pascual-Leone Á.   +8 more
europepmc   +1 more source

AN INTELLIGENT PRIORITY-BASED TELEMEDICINE ALGORITHM FOR REAL-TIME EMERGENCY HEALTH MANAGEMENT IN MILITARY ENVIRONMENTS

DR.S. HEMALATHA, DR. VIJAYA KUMBHAR, SURYA LAKSHMI KANTHAM VINTI, K. PADMAPRIYA, DR.S. MURUGANANDAM, S. K. SATYANARAYANA
openalex   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Polish Translation And Cross-Cultural Adaptation Of The Caregiver Priorities And Child Health Index Of Life With Disabilities Questionnaire.

, 2017
Ewa Matuszczak, Justyna Zielińska-Turek, Wojciech Dębek, Marta Komarowska, Katarzyna Muszyńska‐Rosłan, Jerzy Wojnar, Adam Hermanowicz   +6 more
openalex   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Policy priorities to improve access to advanced practice nursing care for mental health and substance use problems: An American Academy of Nursing manuscript [PDF]

Matthew Tierney, JoEllen Schimmels, Kathleen R. Delaney, Mercy Ngosa Mumba, Derrick Glymph, Cynthia Taylor Handrup, Bethany J. Phoenix   +6 more
openalex   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source